Results 171 to 180 of about 1,865,735 (228)

Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5769-5790, October 2026.
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková   +3 more
wiley   +1 more source

Identification of adducts formed between phosphatidylcholine and mustard agents. [PDF]

open access: yesAnal Bioanal Chem
Kjellberg MA   +4 more
europepmc   +1 more source

Integrating fossil data in ecological niche models to improve predictions of future habitat of Caribbean corals

open access: yesConservation Biology, Volume 40, Issue 5, October 2026.
Abstract Ecological niche models (ENMs) are used to assess the abiotic preferences of species by linking their occurrences to the environmental conditions in which they live. We developed a fossil‐informed ENM framework that integrates mid‐Holocene and modern occurrences to test niche stability and reconstruct abiotic niche characteristics for four ...
Claire. M. Williams   +3 more
wiley   +1 more source

Polymeric Steric Entrapment Synthesis of Compositionally Complex Rare‐Earth Aluminum Garnets (CCREAGs)

open access: yesJournal of the American Ceramic Society, Volume 109, Issue 10, October 2026.
ABSTRACT This work focuses on the polymeric steric entrapment (PSE) technique to synthesize a series of (nRE1/n)3Al5O12, or compositionally complex rare‐earth aluminum garnet (CCREAG) compositions, where RE represents a variety of rare‐earth cations and n is the number of cations occupying the shared position. Using PSE, CCREAGs crystallized at ∼900°C.
Vincent Joseph Garcia   +9 more
wiley   +1 more source

Linking fatty acid composition to enzyme inhibition supported by molecular docking, alongside multifunctional bioactivities, of avocado, Indian mustard, and passion fruit seed oils. [PDF]

open access: yesFront Nutr
Fratianni F   +10 more
europepmc   +1 more source

Probing Subsurface Properties With Mission Hardware: Lessons Learned From Artificial Impacts of Mars 2020

open access: yesGeophysical Research Letters, Volume 53, Issue 18, 28 September 2026.
Abstract Hardware released during spacecraft entry can generate hypervelocity impacts that provide unique constraints on planetary subsurface properties. During NASA's Perseverance descent, two tungsten cruise ballast mass devices (CBMD) and fragments of the cruise stage formed meter‐scale craters north‐west of Jezero crater, in one of the sinuous ...
A. J. Sokołowska   +4 more
wiley   +1 more source

Climate stressor projections inform adaptation needs in South Asian oilseed systems. [PDF]

open access: yesNPJ Sustain Agric
Barik A   +6 more
europepmc   +1 more source

Excessive Convective Precipitation Formation Caused by Warm‐Phase Bulk Microphysical Scheme Biases: A Multi‐Platform Observational Diagnosis

open access: yesJournal of Geophysical Research: Atmospheres, Volume 131, Issue 18, 28 September 2026.
Abstract Recent work has demonstrated that convection‐permitting models often produce a greater number of precipitating convective cells compared to radar observations. Congestus‐depth cells contribute most to the bias, which are colloquially termed “popcorn convection.” This study explores warm‐phase microphysical contributions to the bias using ...
McKenna W. Stanford   +7 more
wiley   +1 more source

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