Results 1 to 10 of about 7,200 (217)

Effect of sulfur mustard on murine lymphocytes

Toxicology Letters, 1991
The effect on spleen cells of a single in vivo treatment with sulfur mustard was analyzed in mice 1 week after intoxication. A marked decrease in the number of total spleen cells was observed in mice receiving high doses of sulfur mustard. Flow cytometric analysis indicated that B-lymphocytes were relatively more affected than T-lymphocytes by this ...
J P, Coutelier, D, Lison, O, Simon, J, Willems   +3 more
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Phenyl sulfur mustard derivatives of distamycin A

Bioorganic & Medicinal Chemistry Letters, 2000
The design, synthesis, and cytotoxic activity of novel benzoyl and cinnamoyl sulfur mustard derivatives of distamycin A are described and structure activity relationships are discussed. These sulfur mustards are more potent cytotoxics than corresponding nitrogen mustards in spite of the lower alkylating power, while their sulfoxide analogues are ...
P. Cozzi, I. Beria, M. Caldarelli, L. Capolongo, C. Geroni, S. Mazzini, E. Ragg   +6 more
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Modeling for immunosupression by sulfur mustard

International Immunopharmacology, 2001
The treatment and cure of patients exposed to sulfur mustard is a remaining challenge despite on-going research in this field. A severe suppression of the immune system still remains the major cause of opportunistic infections, septicemia and death in patients injured by sulfur mustard. In this report, we present a model of sulfur mustard contamination
Z M, Hassan, M, Ebtekar
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Catalytic Processes for the Neutralization of Sulfur Mustard

Chemistry – A European Journal, 2020
AbstractResearch on the decontamination of the chemical warfare agent sulfur mustard pursues several objectives that include the neutralization of spared ammunition, the cleaning of affected areas, and also the development of protective equipment or tools.
Emmanuel Oheix, Edmond Gravel, Eric Doris   +2 more
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Effect of sulfur mustard on melanogenesis in vitro

Toxicology Letters, 2020
The chemical warfare agent sulfur mustard (SM) affects all cells in the epidermis including melanocytes which are responsible for melanin synthesis. After exposure to SM, pigment abnormalities like hypo- and hyperpigmentation can occur. The underlying molecular pathomechanisms of SM exposure on human melanogenesis have not been elucidated so far.
Katharina Müller-Dott, Horst Thiermann, Dirk Steinritz, Tanja Popp   +3 more
openaire   +2 more sources

Agents of chemical warfare: Sulfur mustard

Annals of Emergency Medicine, 1992
Sulfur mustard is a chemical warfare agent of historical and current interest. Favored militarily because of its ability to incapacitate rather than its ability to kill, its use results in large numbers of casualties requiring prolonged, intensive care.
J, Borak, F R, Sidell
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Shapes of Sulfur, Oxygen, and Nitrogen Mustards

The Journal of Physical Chemistry A, 2011
Thorough conformational analyses have been performed on representative sulfur, oxygen, and nitrogen mustards. A total of 23, 18, and 38 unique conformers have been located for SM, OM, and NM, respectively, at the MP2/aug-cc-pVDZ level of theory. Despite the fact that these molecules differ only in the identity of the central heteroatom, comparison of ...
Janos, Nadas, Xiaohua, Zhang, Benjamin P, Hay   +2 more
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Immunological consequence of sulfur mustard exposure

Immunology Letters, 2002
Global reports indicate that chemical weapons still impose a serious threat to world security and health. Sulfur mustard is a chemical compound with devastating short and long-term effect on human health.
Zuhaiar M, Hassan, Massoumeh, Ebtekar
openaire   +2 more sources

Development of an antibody that binds sulfur mustard

Immunology Letters, 1992
An antibody that binds bis(2-chloroethyl) sulfide (sulfur mustard) was developed. The immunizing antigen was prepared from the hapten 4-(2-chloroethyl)benzoic acid covalently bound to keyhole limpet hemocyanin (KLH). The antibody was monitored by a solid phase enzyme-linked immunosorbent assay (ELISA).
C N, Lieske, R S, Klopcic, C L, Gross, J H, Clark, T W, Dolzine, T P, Logan, H G, Meyer   +6 more
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Reaction of elemental sulfur in ethylenediamine with sulfur mustard

Journal of Sulfur Chemistry, 2005
Reaction of elemental sulfur in ethylenediamine with 1,1-thiobis(2-chloroethane) or sulfur mustard, the potent chemical warfare agent has been studied. The optimum conditions for the reaction are established for the complete conversion of sulfur mustard into non-toxic products.
K. Ganesan, R. C. Malhotra, K. Sekhar
openaire   +1 more source