Results 111 to 120 of about 91,791 (263)

Cholesterol Deficiency Directs Autophagy‐Dependent Secretion of Extracellular Vesicles

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
Inhibition of cholesterol biosynthesis within models of rare disease and cancer causes increased release of small extracellular vesicles (sEVs) with distinct biological properties. Mechanistically, cholesterol depletion leads to impaired autophagic flux, redirection of autophagosomes to late endosomes, and subsequently increased sEV secretion ...
Jazmine D. W. Yaeger   +6 more
wiley   +1 more source

Developing of Bacterial Mutagenic Assay System for Detection of Environmental and Food MutagensV – Using Anticancer Drug Cyclophosphamide

open access: yesمجلة بغداد للعلوم, 2008
G-system composed of three isolates G3 ( Bacillus),G12 ( Arthrobacter )and G27 ( Brevibacterium) was used to detect the mutagenicity of the anticancer drug, cyclophosphamide (CP) under conditions similar to that used for standard mutagen ...
Baghdad Science Journal
doaj   +1 more source

Mechanical impacts of climbing on cliff vegetation: Contrasting management concepts

open access: yesPeople and Nature, Volume 8, Issue 1, Page 153-164, January 2026.
Abstract Climbing a boulder for the first time often means entering a previously inaccessible ecosystem, many of which are inhabited by rare species. Little is known about the impacts of first ascents on cliff vegetation, especially with respect to different rock types.
Isabell A. Österle   +4 more
wiley   +1 more source

Lead-induced DNA damage in Vicia faba root cells: Potential involvement of oxidative stress [PDF]

open access: yes, 2011
Genotoxic effects of lead (0–20 µM) were investigated in whole-plant roots of Vicia faba L., grown hydroponically under controlled conditions. Lead-induced DNA damage in V.
Jean, Séverine   +3 more
core   +2 more sources

The human, F-actin-based cytoskeleton as a mutagen sensor

open access: yesCancer Cell International, 2017
Background Forty years ago the actin cytoskeleton was determined to be disrupted in fibroblasts from persons with DNA repair-defective, hereditary colon cancer, with no clear connection between the cytoskeleton and DNA repair defects at that time ...
Nicolette M. Clark   +12 more
doaj   +1 more source

Guidance on the scientific data requirements for an application for authorisation of a food additive submitted under Regulation (EC) No 1331/2008

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract This guidance document applies to applications for a new authorisation as well as for a modification of an existing authorisation of a food additive, submitted under Regulation (EC) No 1333/2008. It defines the scientific data required to evaluate if the food additive is safe under the proposed conditions of use, in accordance with Articles 1 ...
EFSA Panel on Food Additives and Flavourings (FAF)   +30 more
wiley   +1 more source

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. [PDF]

open access: yes, 1984
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat.
Stobo, JD, Weiss, A
core  

Safety evaluation of the modification of the food additive enzymatically produced steviol glycosides (E 960c)

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The EFSA Panel on Food Additives and Flavourings (FAF Panel) provides a scientific opinion on the safety of a modified manufacturing process for the food additive enzymatically produced steviol glycosides (E 960c). The new process converts purified steviol glycosides extracted from Stevia rebaudiana leaves through enzymatic bioconversion ...
EFSA Panel on Food Additives and Flavourings (FAF)   +30 more
wiley   +1 more source

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