Results 111 to 120 of about 91,791 (263)
Cholesterol Deficiency Directs Autophagy‐Dependent Secretion of Extracellular Vesicles
Inhibition of cholesterol biosynthesis within models of rare disease and cancer causes increased release of small extracellular vesicles (sEVs) with distinct biological properties. Mechanistically, cholesterol depletion leads to impaired autophagic flux, redirection of autophagosomes to late endosomes, and subsequently increased sEV secretion ...
Jazmine D. W. Yaeger +6 more
wiley +1 more source
G-system composed of three isolates G3 ( Bacillus),G12 ( Arthrobacter )and G27 ( Brevibacterium) was used to detect the mutagenicity of the anticancer drug, cyclophosphamide (CP) under conditions similar to that used for standard mutagen ...
Baghdad Science Journal
doaj +1 more source
Mechanical impacts of climbing on cliff vegetation: Contrasting management concepts
Abstract Climbing a boulder for the first time often means entering a previously inaccessible ecosystem, many of which are inhabited by rare species. Little is known about the impacts of first ascents on cliff vegetation, especially with respect to different rock types.
Isabell A. Österle +4 more
wiley +1 more source
Lead-induced DNA damage in Vicia faba root cells: Potential involvement of oxidative stress [PDF]
Genotoxic effects of lead (0–20 µM) were investigated in whole-plant roots of Vicia faba L., grown hydroponically under controlled conditions. Lead-induced DNA damage in V.
Jean, Séverine +3 more
core +2 more sources
The human, F-actin-based cytoskeleton as a mutagen sensor
Background Forty years ago the actin cytoskeleton was determined to be disrupted in fibroblasts from persons with DNA repair-defective, hereditary colon cancer, with no clear connection between the cytoskeleton and DNA repair defects at that time ...
Nicolette M. Clark +12 more
doaj +1 more source
Differential Response of Some Tomato Genes to Base-specific Mutagens [PDF]
H. K. Jain, R. N. Raut
openalex +1 more source
Abstract This guidance document applies to applications for a new authorisation as well as for a modification of an existing authorisation of a food additive, submitted under Regulation (EC) No 1333/2008. It defines the scientific data required to evaluate if the food additive is safe under the proposed conditions of use, in accordance with Articles 1 ...
EFSA Panel on Food Additives and Flavourings (FAF) +30 more
wiley +1 more source
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. [PDF]
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat.
Stobo, JD, Weiss, A
core
Abstract The EFSA Panel on Food Additives and Flavourings (FAF Panel) provides a scientific opinion on the safety of a modified manufacturing process for the food additive enzymatically produced steviol glycosides (E 960c). The new process converts purified steviol glycosides extracted from Stevia rebaudiana leaves through enzymatic bioconversion ...
EFSA Panel on Food Additives and Flavourings (FAF) +30 more
wiley +1 more source

