Results 51 to 60 of about 21,085 (189)

The influence of radio-mimetic chemical mutagen on the chromosomal complex of winter wheat cells

open access: yesRegulatory Mechanisms in Biosystems, 2017
In this article we report the results of our investigation of cytogenetic parameters of changes in the chromosomal complex of new Ukrainian winter wheat varieties and some relationships between values of cytological indexes and different concentrations ...
M. M. Nazarenko
doaj   +1 more source

ZIP1 Is a Critical DNA Damage‐Responsive Zinc Transporter Induced by Bleomycin via the TNFα–NF‐κB Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 16, 31 August 2026.
The zinc transporter ZIP1 is induced promptly following treatment with the DNA damage agent bleomycin through the TNFα–NF‐κB pathway. NF‐κB accumulates in the nucleus and upregulates the transcription of SLC39A1, the coding gene for ZIP1. The increased expression of ZIP1 leads to elevated intracellular zinc levels, which, in turn, enhance the DNA ...
Zichong Li   +4 more
wiley   +1 more source

Chromosomal rearrangements caused by gamma-irradiation in winter wheat cells

open access: yesBiosystems Diversity, 2017
In this article we report the results of our investigation into several cytogenetic parameters of variability in mutation induction of modern winter wheat varieties and some connections between the means of cytogenetic indices and different doses of ...
M. M. Nazarenko, O. O. Izhboldin
doaj   +1 more source

EFFECT OF ROCKET JUICE (ERUCA SATIVA ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN FEMUR BONE MARROW CELLS OF WHITE MICE [PDF]

open access: yesMesopotamia Journal of Agriculture, 2008
The effect of orally administered rocket leafs juice on the mitotic index (MI) and micronuclei (Mn) formation was studied in white mice bone marrow . The effect of juice to retarded the abnormalities induced by cyclophosphamide (Cp) administered orally ...
Ilham A. Khalaf
doaj   +1 more source

Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment

open access: yesJournal of Applied Toxicology, Volume 46, Issue 8, Page 2791-2802, August 2026.
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao   +3 more
wiley   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković   +6 more
wiley   +1 more source

Determination of optimum dose of chemical mutagen for large scale seed treatment of white seeded sesame (Sesamum indicum L.) varieties

open access: yesElectronic Journal of Plant Breeding, 2020
In the present study two white seeded sesame varieties VRI 3 and SVPR 1 were treated with seven different concentration viz., 0.2 %, 0.4 %, 0.6 %, 0.8 %, 1 %, 1.2 % and 1.4 % of chemical mutagen Ethyl Methane Sulphonate (EMS).
V. Sandhiya, M. Kumar, C. Parameswari, C. Vanniarajan, N. Kumaravadivel, N. Sakthivel and Anand M. Badigannavar
doaj   +1 more source

Towards Bio‐Based Benzoxazines (2015–2025): A Critical Review of Renewable Building Blocks, Formaldehyde‐Free Aldehydes, and ECHA Hazard Landscape

open access: yesPolymers for Advanced Technologies, Volume 37, Issue 8, August 2026.
ABSTRACT This review provides a critical overview of research on fully bio‐based benzoxazines over the period 2015–2025. A bibliometric analysis based on the Web of Science database is used to map how the field has evolved and to identify the renewable building blocks that have been most widely adopted.
Elizabeth Alvarez Perez, Alice Mija
wiley   +1 more source

Maize Biofortification Approaches for Fighting Malnutrition in Sub‐Saharan Africa

open access: yesPlant-Environment Interactions, Volume 7, Issue 4, August 2026.
ABSTRACT Maize is a staple food in sub‐Saharan Africa (SSA); however, commonly used maize varieties are deficient in essential nutrients, including lysine, tryptophan, vitamin A, and minerals such as iron (Fe) and zinc (Zn). As a result, millions of people in this region suffer from one or more nutrient deficiencies that commonly lead to malnutrition ...
Bitew Tilahun Engida   +2 more
wiley   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha ( Withania somnifera )

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 5030-5047, August 2026.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan   +2 more
wiley   +1 more source

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