Results 291 to 300 of about 664,651 (329)
Structure of the G<sub>q</sub>-coupled adhesion receptor ADGRL4. [PDF]
Nat CommunChen Q +6 more
europepmc +1 more source
Mutation of a conserved anthranilate phosphoribosyltransferase active site residue supports tryptophan biosynthesis <i>in vivo</i>. [PDF]
MicroPubl BiolKlepin S, Michalik B, Pillus L, Chik JK.
europepmc +1 more source
The new era of bioengineered plant NLR receptors. [PDF]
Plant CommunCao P +5 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Current Opinion in Genetics & Development, 1993
In Escherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires some form of DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. An analysis of SOS mutagenesis offers insights into the molecular basis of induced mutagenesis and into mechanisms of DNA damage tolerance.
S, Murli, G C, Walker
openaire +2 more sources
In Escherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires some form of DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. An analysis of SOS mutagenesis offers insights into the molecular basis of induced mutagenesis and into mechanisms of DNA damage tolerance.
S, Murli, G C, Walker
openaire +2 more sources
2005
To identify new genes in an organism, a genetic approach can be used to screen for mutations that display a particular phenotype. Genotoxic agents, such as ultraviolet (UV) light, ionizing radiation, or chemicals can be used to randomly induce DNA lesions in the genome.
Leslie, Barbour +2 more
openaire +2 more sources
To identify new genes in an organism, a genetic approach can be used to screen for mutations that display a particular phenotype. Genotoxic agents, such as ultraviolet (UV) light, ionizing radiation, or chemicals can be used to randomly induce DNA lesions in the genome.
Leslie, Barbour +2 more
openaire +2 more sources
Methods, 2004
Mutagenesis represents a powerful methodology for the analysis of protein structural and functional relationships and dissection of complex protein-protein interactions. The suicide substrate-like inhibitory mechanism of the proteins of the serpin superfamily offers unique challenges for the design of mutagenesis studies.
Toni M, Antalis, Daniel A, Lawrence
openaire +2 more sources
Mutagenesis represents a powerful methodology for the analysis of protein structural and functional relationships and dissection of complex protein-protein interactions. The suicide substrate-like inhibitory mechanism of the proteins of the serpin superfamily offers unique challenges for the design of mutagenesis studies.
Toni M, Antalis, Daniel A, Lawrence
openaire +2 more sources
Methods in cell biology, 1996
Choosing the right mutagen means selecting the right combination of mutagen efficiency and mutagen specificity. For mutagen efficiency, nothing beats EMS. It is extremely potent, it is easy to use, and its mutational specificity is well documented. If mutations other than G/C-->A/T transitions are desired, mutagens other than EMS must be used. Based on
M. S. Clark, W. J. Wall
openaire +3 more sources
Choosing the right mutagen means selecting the right combination of mutagen efficiency and mutagen specificity. For mutagen efficiency, nothing beats EMS. It is extremely potent, it is easy to use, and its mutational specificity is well documented. If mutations other than G/C-->A/T transitions are desired, mutagens other than EMS must be used. Based on
M. S. Clark, W. J. Wall
openaire +3 more sources
Biological Reviews, 1949
SummaryThe general methodological requirements for work with chemical mutagens are the same as for general mutation work, with special emphasis on questions of concentration, penetration, possible indirect or delayed effect, differences in susceptibility between individuals, strains and species.
openaire +2 more sources
SummaryThe general methodological requirements for work with chemical mutagens are the same as for general mutation work, with special emphasis on questions of concentration, penetration, possible indirect or delayed effect, differences in susceptibility between individuals, strains and species.
openaire +2 more sources
2014
Transposon-based mutagenesis of bacterial genomes is a powerful method to identify genetic elements that control specific phenotypes. The most frequently used transposon tools in Pseudomonas aeruginosa are based either on Himar1 mariner or Tn5 transposases, both of which have been used to generate nonredundant mutant libraries in P. aeruginosa. Here we
openaire +2 more sources
Transposon-based mutagenesis of bacterial genomes is a powerful method to identify genetic elements that control specific phenotypes. The most frequently used transposon tools in Pseudomonas aeruginosa are based either on Himar1 mariner or Tn5 transposases, both of which have been used to generate nonredundant mutant libraries in P. aeruginosa. Here we
openaire +2 more sources