Results 11 to 20 of about 49,008 (223)
Optimal doses and concentrations of mutagens for winter wheat breeding purposes. Part I. Grain productivity [PDF]
Evaluation of winter wheat mutant families (2011 – 2012, second – third generations, exclude a little number of dominant mutations at first generation) and lines (2013 – 2016, forth and next generations) has been carried out.
Mykola Nazarenko+3 more
doaj +2 more sources
Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine. [PDF]
A method is described for concentrating mutagens/carcinogens from human urine about 200-fold for subsequent assay in the Salmonella/mammalian microsome mutagenicity test.
Edna N. Yamasaki, B N Ames
openalex +2 more sources
Unboxing the molecular modalities of mutagens in cancer
The etiology of the majority of human cancers is associated with a myriad of environmental causes, including physical, chemical, and biological factors. DNA damage induced by such mutagens is the initial step in the process of carcinogenesis resulting in
S. Kumari+5 more
semanticscholar +1 more source
Polycyclic aromatic compounds (PACs) are known due to their mutagenic activity. Among them, 2-nitrobenzanthrone (2-NBA) and 3-nitrobenzanthrone (3-NBA) are considered as two of the most potent mutagens found in atmospheric particles. In the present study
A. G. Santos+2 more
semanticscholar +1 more source
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test.
J. McCann, E. Choi, E. Yamasaki, B. Ames
semanticscholar +1 more source
18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are shown to be activated by liver homogenates to form potent frameshift mutagens.
B. Ames, W. Durston, E. Yamasaki, F. Lee
semanticscholar +1 more source
It is difficult to identify mutagen-induced genome-wide somatic mutations using next generation sequencing; hence, mutagenic features of each mutagen and their roles in cancer development require further elucidation.
S. Matsumura+5 more
semanticscholar +1 more source
Replication errors influence mutations, and thus, lifetime cancer risk can be explained by the number of stem-cell divisions. Additionally, mutagens also affect cancer risk, for instance, high-dose radiation exposure increases lifetime cancer risk ...
Kouki Uchinomiya, Masanori Tomita
doaj +1 more source
Principle and application of plant mutagenesis in crop improvement: a review
The first step in plant breeding is to identify suitable genotypes containing the desired genes among existing varieties, or to create one if it is not found in nature.
Yusuff Oladosu+7 more
doaj +1 more source
Induced Mutations Unleash the Potentials of Plant Genetic Resources for Food and Agriculture
The options for increasing food production by at least 70% over the next four decades so as to keep pace with a rapidly increasing human population are bedeviled by erratic climatic conditions, depleted arable lands, dwindling water resources and by the ...
Chikelu Mba
doaj +1 more source