Results 151 to 160 of about 2,828,087 (336)
Análise dos mutantes de leveduras Saccharomyces cerevisiae para melhoria na resistência e produção de etanol [PDF]
, 2013 André de Abreu Cavalheiro
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Mutants and SU(3)_q invariants [PDF]
, 1998 Details of quantum knot invariant calculations using a specific SU(3)_q-module are given which distinguish the Conway and Kinoshita-Teresaka pair of mutant knots. Features of Kuperberg's skein-theoretic techniques for SU(3)_q invariants in the context of
Morton, H. R., Ryder, H. J.
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Constraints of FL Motif on the Targeting and Function of Sodium-Bicarbonate Cotransporter 1 [PDF]
, 2008 A C-terminal dihydrophobic FL motif plays a vital role in the basolateral targeting of sodium bicarbonate cotransporter 1. To further characterize the role of dihydrophobic FL motif, 1). the FL motif in wild type (PFLS) was reversed to LF (PLFS), 2). the
Ali Shawki +7 more
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Prohibitin depletion extends lifespan of a TORC2/SGK‐1 mutant through autophagy and the mitochondrial UPR [PDF]
, 2021 Patricia de la Cruz Ruiz +7 more
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Estudos estruturais e funcionais do fator inibitório da migração dos macrófagos de >i<Leishmania major>/i< (L>i<m>/i<MIF2) e de mutantes da região Carboxi-terminal [PDF]
, 2019 Elise Marques Freire Cunha
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Regio‐ and stereo‐selective 1β‐hydroxylation of lithocholic acid by cytochrome P450 BM3 mutants [PDF]
, 2023 Haiyan Li +5 more
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source