Results 261 to 270 of about 2,828,087 (336)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Arabidopsis PIEZO Regulates Root Growth in Response to Magnetic Field and Blue Light Signaling. [PDF]

Physiol Plant
Peng Z, Yang W, Dong M, Bai H, Zhao W, Pan N, Lei Y, Zhu Z, Wan Y, Xie Y, Guo L, Peng S, Liu C, Du Y.   +13 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Integrative Transcriptomic and Phosphoproteomic Analysis Reveals Key Components of the SnRK1 Signaling Network in Rice. [PDF]

Plant Direct
Faria-Bates MC, Maurya C, Muhammed Jamsheer K, Srivastava V.   +3 more
europepmc   +1 more source

Characteristics of H3 K27M-mutant gliomas in adults

Neuro-Oncology, 2017
D. Meyronet, Maud Esteban-Mader, C. Bonnet, M. Joly, E. Uro-Coste, A. Amiel-Benouaich, Fabien Forest, C. Rousselot-Denis, F. Burel-Vandenbos, V. Bourg, J. Guyotat, T. Fenouil, A. Jouvet, J. Honnorat, F. Ducray   +14 more
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Prognosis and treatment response stratification according to loss of proofreading (LOP) <i>POLE</i> variants. [PDF]

J Immunother Cancer
Maddalena G, Zeineddine FA, Chowdhury S, Zeineddine MA, Yousef AM, Bergamo F, Lonardi S, Yap TA, White MG, Overman MJ, Kopetz S, Shen JP.   +11 more
europepmc   +1 more source

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

Cancer Cell, 2005
E. Weisberg, P. Manley, W. Breitenstein, J. Brüggen, S. Cowan-Jacob, A. Ray, B. Huntly, D. Fabbro, G. Fendrich, Elizabeth Hall-Meyers, A. Kung, A. Kung, J. Mestan, G. Daley, Linda L. Callahan, L. Catley, C. Cavazza, Azam Mohammed, D. Neuberg, R. Wright, D. Gilliland, J. Griffin   +21 more
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

A systematic review and meta-analysis of effect of mutant traits in chickens. [PDF]

Trop Anim Health Prod
Mhlabini S, Tyasi TL, Nemutandani KR.
europepmc   +1 more source