Results 271 to 280 of about 2,913,254 (384)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in <i>MYOD1</i>-mutant rhabdomyosarcoma. [PDF]

Sci Adv
Dermawan JK, Vanoli F, de Traux de Wardin H, Levi JN, Sanchez GI, Siddiquee A, Brosius S, You D, Tirode F, Sung P, Karanian M, Pissaloux D, Wexler LH, Kung A, Soragni A, Dela Cruz FS, Pavisic J, Antonescu CR.   +17 more
europepmc   +1 more source

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

Cancer Cell, 2005
E. Weisberg, P. Manley, W. Breitenstein, J. Brüggen, S. Cowan-Jacob, A. Ray, B. Huntly, D. Fabbro, G. Fendrich, Elizabeth Hall-Meyers, Andrew L. Kung, Andrew L. Kung, J. Mestan, G. Daley, Linda L. Callahan, L. Catley, C. Cavazza, Azam Mohammed, D. Neuberg, R. Wright, D. Gilliland, J. Griffin   +21 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

AMBIVALENT rII MUTANTS OF PHAGE T4

, 1961
Seymour Benzer, Sewell P. Champe
openalex   +2 more sources

MUTANTS IN HABROBRACON

Genetics, 1932
openaire   +2 more sources

Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.

Developmental Cell, 2015
Fatma Kok, M. Shin, C. Ni, Ankit Gupta, Ann S. Grosse, A. V. Impel, Bettina C. Kirchmaier, J. Peterson-Maduro, George Kourkoulis, I. Male, Dana F DeSantis, Sarah Sheppard-Tindell, Lwaki Ebarasi, Lwaki Ebarasi, Christer Betsholtz, Christer Betsholtz, S. Schulte-Merker, S. Wolfe, N. Lawson   +18 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Corrigendum to 'Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer': [ESMO Open. Volume 11, Issue 2, February 2026, 106057]. [PDF]

ESMO Open
Lee JB, Kim KH, Yoon S, Song SY, Lee SS, Jo S, Ahn HK, Kim HJ, Choi SJ, Park H, Hong MH, Cho BC, Yoon HI, Lim SM.   +13 more
europepmc   +1 more source