Results 311 to 320 of about 2,828,087 (336)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

An injectable hydrogel containing <i>N</i>-acetylglycine for the treatment of Gaucher disease. [PDF]

RSC Adv
Pradhan L, Manna S, Yadav AJ, Bajrang B, Chakraborty D, Bhagat K, Tripathi S, Parmar AS, Padhi AK, Mukherjee S.   +9 more
europepmc   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Structural and functional impact of the POLD1 Ser605del variant in MDPL syndrome: insights from protein-protein interactions. [PDF]

Hum Genomics
Murdocca M, Romeo I, Maccaroni S, Curcio A, Pepe G, Helmer-Citterich M, Alcaro S, Novelli G, Sangiuolo F.   +8 more
europepmc   +1 more source

Novel amino acid residues in listerolysin O drive phagosome escape and pathogenicity in <i>Listeria monocytogenes</i>. [PDF]

Virulence
Xia J, Feng Y, Xu J, Deng S, Chen M, Han Y, Wang J, Sun J, Rantsiou K, Cocolin LS, Song H, Cheng C.   +11 more
europepmc   +1 more source

CRISPR with a Double Mismatch Guide RNA Enhances Detection Sensitivity for Low-Frequency Single-Base EGFR Mutation in Circulating Cell-Free DNA of Lung Cancer Patients. [PDF]

Cancers (Basel)
Been KW, Kang S, Bae T, Hong S, Kim G, Hur JK, Hwang W, Chang B.   +7 more
europepmc   +1 more source

Mutant allele formation and inheritance during Cas9/guide RNA-mediated gene drive in a population modification mosquito strain for human malaria control. [PDF]

Genetics
Carballar-Lejarazú R, Pham TB, Tushar T, James AA.   +3 more
europepmc   +1 more source

IDH mutations are rare events in SHH medulloblastoma. [PDF]

Acta Neuropathol
Fürst A, Ruf V, Fiedler C, Rutkowski S, Sill M, Korshunov A, Gerber NU, Frank S, Hench J, Schüller U.   +9 more
europepmc   +1 more source