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Mutants of Apolipoproteins A and C

1986
The determination of the circulating levels of apolipoproteins has become common practice in clinical laboratories, in view of the apparent correlation between levels of specific apolipoproteins and increased or decreased cardiovascular risk [1, 2].
C. R. Sirtori, M. R. Lovati
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Mutant Proteogenomics

2016
Identification of mutant proteins in biological samples is one of the emerging areas of proteogenomics. Despite the fact that only a limited number of studies have been published up to now, it has the potential to recognize novel disease biomarkers that have unique structure and desirably high specificity.
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Construction of LPS Mutants

2003
Lipopolysaccharide (LPS) is a major component of the meningococcal outer membrane. It consists of a hexa-acylated glucosamine disaccharide substituted at both ends with diphosphoethanolamine, to which an oligosaccharide chain of up to 10 sugar residues is attached (1,2).
van der Ley, Privm, Steeghs, L
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Dynamics of escape mutants

Theoretical Population Biology, 2007
We use multi-type Galton-Watson branching processes to model the evolution of populations that, due to a small reproductive ratio of the individuals, are doomed to extinction. Yet, mutations occurring during the reproduction process, may lead to the appearance of new types of individuals that are able to escape extinction.
Serra, Maria Conceição, Haccou, Patsy
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Cell wall mutants

Plant Physiology and Biochemistry, 2000
An ever growing collection of cell wall mutants is yielding new insights into the mechanisms underlying the synthesis and assembly of cell walls in plants. In this review, we will provide an update on the use of genetic tools in plant cell wall research and we will discuss the lessons that can be drawn from the study of the first generation of mutants.
Fagard, Mathilde   +2 more
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Mutants and Monsters

2011
Science fiction films of the 50s, the period when nuke-awareness was at its height, are full of monsters. And the monsters tend to be radioactive. Peter Biskind, quoted above, tries to reduce the monster movies of the 50s to expressions of the oldest theme in the horror cannon, nature run amok, but monsters are rarely as simple as they at first seem ...
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RNA editing mutants as surrogates for mitochondrial SNP mutants

Plant Physiology and Biochemistry, 2019
In terrestrial plants, RNA editing converts specific cytidines to uridines in mitochondrial and plastidic transcripts. Most of these events appear to be important for proper function of organellar encoded genes, since translated proteins from edited mRNAs show higher similarity with evolutionary conserved polypeptide sequences. So far about 100 nuclear
Anja Jörg   +3 more
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Construction of porA Mutants

2003
The PorA or class 1 protein is one of the major meningococcal outermembrane proteins (OMPs). It is one of the two porins found in this organism, the other one being the PorB or class 2/3 protein. It folds into a 16-stranded β-barrel structure, which is now well-established for bacterial porins, in which seven loops are exposed at the cell surface and ...
van der Ley, Privm, van Alphen, L
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Membrane Mutants: A Yeast Mutant with a Lesion in Phosphatidylserine Biosynthesis

European Journal of Biochemistry, 1980
A single‐gene nuclear choline‐requiring mutant of Saccharomyces cerevisiae was studied. Choline as a growth supplement to synthetic media could be substituted by low concentrations of d imethylethanolamine, monomethylethanolamine or ethanol amine. DL‐Serine also supported growth, but only at high concentrations: on a molar basis it was approximately ...
Ladistav Kováč   +4 more
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Ochre mutants, a new class of suppressible nonsense mutants

Journal of Molecular Biology, 1965
Suppressors of a strongly polar mutant of the lac gene in Escherichia coli also suppress mutants of the rII genes of bacteriophage T4. Included amongst this set are some amber mutants, but there are also many other mutants which are not suppressed by amber suppressors. These mutants are denned as ochre mutants, and the suppressors as ochre suppressors.
Sydney Brenner, Jon Beckwith
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