Results 321 to 330 of about 2,913,254 (384)

A proposal for expedited stem cell transplantation for TP53-mutant myelodysplastic neoplasms and acute myeloid leukemia. [PDF]

Blood Adv
Patel SA, Devine SM, Cerny J.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

XRE-type transcriptional regulator ProR controls prodigiosin synthesis in <i>Serratia marcescens</i> JNB5-1. [PDF]

Synth Syst Biotechnol
Tang M, Hao Y, Zhao Y, Li Y, You J, Yang T, Pan X, Rao Z.   +7 more
europepmc   +1 more source

Essential role of cytochrome <i>bc</i> ₁ in <i>Pseudomonas aeruginosa</i> cell physiology and virulence. [PDF]

Front Cell Infect Microbiol
Sorescu JM, González-Montalvo MA, Patel N, Baltes G, Avula SR, Tuz K, Juárez OX.   +6 more
europepmc   +1 more source

PINCH proteins orchestrate vascular mural cell homeostasis through integrated signaling and transcriptional networks. [PDF]

Angiogenesis
Wang C, Jin Y, Xin Y, Xing Q, Zhu H, Zou Q, Yan J, Luo L, Liang X, Sun Y, Liu Z.   +10 more
europepmc   +1 more source

Mutant

, 1966
openaire   +1 more source

Selective silencing of expanded CAG repeats: Chemically modified siRNA advances RNA-based therapies for polyglutamine diseases. [PDF]

Mol Ther Nucleic Acids
Scholten GJ, Hyde JT, Buijsen RAM.
europepmc   +1 more source