Molecular Modelling-Based Investigations of a Mutant Protein in Patients with Hearing Loss
Kazunori Namba
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Prediction on the risk population of idiosyncratic adverse reactions based on molecular docking with mutant proteins. [PDF]
Xie H +8 more
europepmc +1 more source
1I1045 Recent developments in ProTherm : Thermodynamic Database for Proteins and Mutants
Abdulla Bava Kuttunganakam +4 more
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Biophysical, Biochemical, and Physiological Characterization ofChlamydomonas reinhardtii Mutants with Amino Acid Substitutions at the Ala251 Residue in the D1 Protein That Result in Varying Levels of Photosynthetic Competence [PDF]
Anita Lardans +8 more
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Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Not So Rare: Diseases Based on Mutant Proteins Controlling Endoplasmic Reticulum-Mitochondria Contact (MERC) Tethering. [PDF]
Makio T, Simmen T.
europepmc +1 more source
Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins. [PDF]
White KA +6 more
europepmc +1 more source
The Genes for Myelin Basic Protein in Normal and Shiverer Mutant Mice
Arthur Roach
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