Results 31 to 40 of about 8,186,126 (347)
Scientific Reports, 2015 Although the thermodynamics of protein denaturation at temperatures over 100 °C is essential for the rational design of highly stable proteins, it is not understood well because of the associated technical difficulties.
Y. Matsuura +7 more
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Conformational stability of adrenodoxin mutant proteins [PDF]
Protein Science, 1996 AbstractAdrenodoxin and the mutants at the positions T54, H56, D76, Y82, and C95, as well as the deletion mutants 4–114 and 4–108, were studied by high‐sensitivity scanning microcalorimetry, limited proteolysis, and absorption spectroscopy. The mutants show thermal transition temperatures ranging from 46 to 56 °C, enthalpy changes from 250 to 370 kJ ...
Pfeil, Wolfgang +5 more
openaire +4 more sources
Mutant p53 : One, No One and One Hundred Thousand
Frontiers in Oncology, 2015 Encoded by the mutated variants of the TP53 tumor suppressor gene, mutant p53 proteins are getting an increased experimental support as active oncoproteins promoting tumor growth and metastasis.
Dawid eWalerych +4 more
doaj +1 more source
JC virus small T antigen binds phosphatase PP2A and Rb family proteins and is required for efficient viral DNA replication activity. [PDF]
PLoS ONE, 2010 The human polyomavirus, JC virus (JCV) produces five tumor proteins encoded by transcripts alternatively spliced from one precursor messenger RNA. Significant attention has been given to replication and transforming activities of JCV's large tumor ...
Brigitte Bollag +3 more
doaj +1 more source
In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]
, 2015 The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra +5 more
core +1 more source
Journal of Biological Chemistry, 2015 Background: 20 read-through mutations that produce C-terminally extended proteins are related to human hereditary disorders. Results: The C-terminal extended proteins of mouse cFLIP-L (cellular FLICE-like apoptosisinhibitory protein) and human PNPO ...
N. Shibata +10 more
semanticscholar +1 more source
Analysis of mutant Ras proteins [PDF]
Biochemistry and Molecular Biology Education, 2007 AbstractTerms to be familiar with before you start to solve the test: growth‐factor signaling; Ras proteins; Raf proteins; G proteins; protein kinases; GTPase; GEFs (guanine nucleotide exchange factors); GAPs (GTPase activating proteins); transfection; expression plasmid; mitogen‐activated protein kinase (MAPK); extracellular signal‐regulated kinase ...
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Mutant MotB proteins in Escherichia coli [PDF]
Journal of Bacteriology, 1991 The MotB protein of Escherichia coli is an essential component in each of eight torque generators in the flagellar rotary motor. Based on its membrane topology, it has been suggested that MotB might be a linker that fastens the torque-generating machinery to the cell wall.
D F, Blair, D Y, Kim, H C, Berg
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Transcriptome analysis of the epidermis of the purple quail-like (q-lp) mutant of silkworm, Bombyx mori. [PDF]
PLoS ONE, 2017 A new purple quail-like (q-lp) mutant found from the plain silkworm strain 932VR has pigment dots on the epidermis similar to the pigment mutant quail (q).
Pingyang Wang +5 more
doaj +1 more source
Cells, 2023 Several antimicrobial peptides suppress the growth of lymph gland (LG) tumors in Drosophila multi sex comb (mxc) mutant larvae. The activity of another family of polypeptides, called Turandots, is also induced via the JAK/STAT pathway after bacterial ...
Yuriko Kinoshita +3 more
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