Results 211 to 220 of about 3,006,553 (325)
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Information dynamics and the emergence of high-order individuality in ecosystems. [PDF]
Rajpal H+6 more
europepmc +1 more source
Induced Host-Range Mutations in Bacteriophage [PDF]
Bernal Fernandez+2 more
openalex +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data. [PDF]
Kang S+7 more
europepmc +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
CONTRIBUTION TO THE HISTORY OF A MUTATION DURING 1,000,000 YEARS
Björn Kurtén
openalex +1 more source
The Researches of Bouvier and Bordage on Mutations in Crustacea of the Family Atyidæ [PDF]
W. T. Calman
openalex +1 more source