Mutation-acyclic quivers are totally proper [PDF]
arXivTotally proper quivers, introduced by S.~Fomin and the author arXiv:2406.03604, have many useful properties including powerful mutation invariants. We show that every mutation-acyclic quiver (i.e., a quiver that is mutation equivalent to an acyclic one) is totally proper. This yields new necessary conditions for a quiver to be mutation-acyclic.
arxiv
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
THE QUANTITATIVE ESTIMATION OF RADIATION INDUCED MUTATIONS TO STREPTOMYCIN RESISTANCE IN ESCHERICHIA COLI [PDF]
, 1954 B. A. Rubin
openalex +1 more source
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
New England Journal of Medicine, 2017 R. Stone +28 more
semanticscholar +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
On Accelerating Deep Neural Network Mutation Analysis by Neuron and Mutant Clustering [PDF]
arXivMutation analysis of deep neural networks (DNNs) is a promising method for effective evaluation of test data quality and model robustness, but it can be computationally expensive, especially for large models. To alleviate this, we present DEEPMAACC, a technique and a tool that speeds up DNN mutation analysis through neuron and mutant clustering ...
arxiv
Production of lethal mutations in the fungus Chætomium globosum by monochromatic ultra-violet irradiation [PDF]
, 1949 A. L. McAulay +2 more
openalex +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Eine neue Mutation in der Ommochrombildungskette bei Ephestia kühniella [PDF]
, 1957 Alfred Kühn
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source