Results 221 to 230 of about 4,355,944 (375)

NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors

, 2020
Romel Somwar, Nicolle E. Hofmann, Bryan D. Smith, Igor Odintsov, Morana Vojnic, Irina Linkov, Ashley Tam, Inna Khodos, Marissa S. Mattar, Elisa de Stanchina, Daniel L. Flynn, Marc Ladanyi, Alexander Drilon, Ujwal Shinde, Monika A. Davare   +14 more
openalex   +1 more source

Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules

, 2023
Yuxuan Wang, Christopher Douville, Joshua D. Cohen, Austin K. Mattox, Sam Curtis, Natalie Silliman, Maria Popoli, Janine Ptak, Lisa Dobbyn, Nadine Nehme, Jonathan C. Dudley, Mahmoud Summers, Ming Zhang, Lan T. Ho‐Pham, Ngoc Bich Tran, Thach Tran, Tuan V. Nguyen, Chetan Bettegowda, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein   +20 more
openalex   +1 more source

Patterns of somatic mutation in human cancer genomes

Nature, 2007
Michael R. Stratton
semanticscholar   +1 more source

Mutator Mutation in Carcinogenesis.

Kagaku To Seibutsu, 1996
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Prediction of EGFR mutation status and mutation sites in lung cancer based on radiomics and deep learning. [PDF]

J Thorac Dis
Zeng Z, Zhang R, Dong Y, Liu B, Ma H, Zheng Y, Gao X, Li Q.   +7 more
europepmc   +1 more source

Modeling, Molecular Dynamics Simulation, and Mutation Validation for Structure of Cannabinoid Receptor 2 Based on Known Crystal Structures of GPCRs

, 2014
Zhiwei Feng, Mohammed H. Alqarni, Peng Yang, Qin Tong, Anandã Chowdhury, Lirong Wang, Xiang‐Qun Xie   +6 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Large DNA and protein language models enhance discovery of deleterious mutations in maize. [PDF]

Genome Biol
Wang Y, He C, Wang Q, Li R, Qin Y, Wang H, Gou M, Zhang X, Li H, Huang Q, Liu X, Yang J, White FF, Fu J, Liu S, Zheng J.   +15 more
europepmc   +1 more source

How do mutations affecting the breast cancer genes BRCA1 and BRCA2 cause cancer susceptibility?

, 2019
Ashok R. Venkitaraman
openalex   +2 more sources