Results 21 to 30 of about 1,662,601 (323)
We study mutations of Conway-Coxeter friezes which are compatible with mutations of cluster-tilting objects in the associated cluster category of Dynkin type $A$. More precisely, we provide a formula, relying solely on the shape of the frieze, describing how each individual entry in the frieze changes under cluster mutation.
Baur, Karin+4 more
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A mutation cycle is a cycle in a graph whose vertices are labeled by the quivers in a given mutation class and whose edges correspond to single mutations. For any fixed $n\ge 4$, we describe arbitrarily long mutation cycles involving $n$-vertex quivers.
arxiv
This Article contains errors in Fig. 3, Fig. 4 and Fig. 7, for which we apologize. In Fig. 3, panel ‘b’, the 0.5 hour time point after Ku55933 treatment images were inadvertently replaced with duplicates of the 3 hour time point after Ku55933 treatment ...
Jung-Hee Lee+11 more
doaj +1 more source
A Spatial Mutation Model with Increasing Mutation Rates [PDF]
We consider a spatial model of cancer in which cells are points on the $d$-dimensional torus $\mathcal{T}=[0,L]^d$, and each cell with $k-1$ mutations acquires a $k$th mutation at rate $\mu_k$. We will assume that the mutation rates $\mu_k$ are increasing, and we find the asymptotic waiting time for the first cell to acquire $k$ mutations as the torus ...
arxiv
Mutation Spectra and the Neutrality of Mutations [PDF]
The effect of amino acid replacements on enzyme function was studied in the tJ-galactosidase of Escherichia coli. Mutants possessing 50% or less of normal enzyme activity were isolated and examined. Of 733 amino acid substitutions calculated to have occurred, only 11 reduced tJ-galactosidase activity below 50 %.
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Background Up to 80% of cases of prostate cancer present with multifocal independent tumour lesions leading to the concept of a field effect present in the normal prostate predisposing to cancer development.
Claudia Buhigas+26 more
doaj +1 more source
Concordance and mutation [PDF]
Published in Geometry and Topology at http://www.maths.warwick.ac.uk/gt/GTVol5/paper26.abs ...
Kirk, Paul A, Livingston, Charles
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ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
MDC1 is a key component of the DNA damage response and interacts with several factors such as γ-H2AX. Here the authors show that MDC1 interacts with ID3, facilitating MDC1 recruitment to sites of damage and repair of breaks.
Jung-Hee Lee+11 more
doaj +1 more source
Mutagenic effectiveness and efficiency are the most important factors determining the success of mutation breeding, a coherent tool for quickly enhancing genetic diversity in crops. However, conclusive evidence of using an effective and efficient dose of
Aamir Raina+5 more
doaj +1 more source