Results 41 to 50 of about 87,531 (297)

Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values

, 2009
The aim of this paper was to compare the effect of haplotype definition on the precision of QTL-mapping and on the accuracy of predicted genomic breeding values.
Veerkamp Roel F, Theo HE Meuwissen, Egbert F Knol, Addie LJ Vereijken, Calus Mario PL, Vereijken Addie LJ, Knol, E.F., Schrooten, C., Windig, J.J., Meuwissen Theo HE, Knol Egbert F, Calus, M.P.L., Vereijken, A.L.J., Roel F Veerkamp, Jack J Windig, Windig Jack J, Veerkamp, R.F., Chris Schrooten, Schrooten Chris, Meuwissen, T.H.E., Mario PL Calus   +20 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Effects of 60Co-γ Ray Irradiation on the Quality of Ponkan Peels [PDF]

Shipin Kexue
To investigate the effect of different doses of 60Co-γ ray irradiation on the quality of ponkan peels, the major functional components of irradiated ponkan peels were determined by ultraviolet-visible (UV-Vis) spectrophotometry and high performance ...
WANG Xue, PAN Zhaoping, LI Wenge, SU Zhipeng, CHEN Jiaxu, HE Shuang, FU Fuhua
doaj   +1 more source

Construction of Soybean Mutant Diversity Pool (MDP) Lines and an Analysis of Their Genetic Relationships and Associations Using TRAP Markers

Agronomy, 2020
Mutation breeding is useful for improving agronomic characteristics of various crops. In this study, we conducted a genetic diversity and association analysis of soybean mutants to assess elite mutant lines.
Dong-Gun Kim, Jae Il Lyu, Min-Kyu Lee, Jung Min Kim, Nguyen Ngoc Hung, Min Jeong Hong, Jin-Baek Kim, Chang-Hyu Bae, Soon-Jae Kwon   +8 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Field and laboratory assessments of sugarcane mutants selected in vitro for resistance to imazapyr herbicide [PDF]

Crop Breeding and Applied Biotechnology, 2017
Seven imazapyr-tolerant mutant sugarcane plants, previously generated by in vitro mutagenesis, were studied. The imazapyr concentrations required to inhibit their acetolactate synthase (ALS basal activity) (IC50 as μmoles acetoin h-1 mg-1 protein) were 0.
RS Rutherford, KZ Maphalala, AC Koch, SJ Snyman, MP Wat   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Implementation of two high through-put techniques in a novel application: detecting point mutations in large EMS mutated plant populations

, 2009
Background - The establishment of mutant populations together with the strategies for targeted mutation detection has been applied successfully to a large number of organisms including many species in the plant kingdom.
Hermans, F.W.K., Bachem, C.W.B., Eibertus N van Loo, van Loo, E.N., Marion HBJ Van de Wal, Freddy WK Hermans, Richard GF Visser, Loo, E.N., van, Visser, R.G.F., Antoine LF Gady, Christian WB Bachem, Gady, A.L.F., Wal, M.H.B.J., van de, van de Wal, M.H.B.J.   +13 more
core   +1 more source

Evaluation of Grain Yield and Yield Stability in Rapeseed (Brassica Napus) Mutant Lines Using GGE Biplot [PDF]

مجله علوم و فنون هسته‌ای, 2018
In order to evaluate the mutant lines derived from irradiation of oilseed rape cultivar RGS003 using gamma-ray, this study was carried out during two growing seasons from 2011 to 2013, at the experimental fields in the Nuclear Agricultural Research ...
B Naserian Khiabani, B Alizadeh
doaj   +1 more source

Performance Evaluation of Induced Mutagenesis using Colchicine and EMS Solution on Cowpea M3 Purple and Mung Bean Vima1 to Increase Resistance

Caraka Tani: Journal of Sustainable Agriculture, 2022
Induced mutagenesis is one way to improve the quality of crops, especially to increase the resistance to pests and diseases. This research aimed to determine colchicine and ethyl methane sulfonate (EMS) mutagenesis on cowpea M3 purple and mung bean Vima1,
I Gede Ketut Susrama, Ni Made Trigunasih, I ketut Suada, Ni Nyoman Ari Mayadewi   +3 more
doaj   +1 more source