Results 271 to 280 of about 199,597 (317)

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Melanoma-specific survival and relapse-free survival are significantly improved for tumors with high tumor mutational burden and BRAF V600 mutation – results of 83 stage IIIC-IV patients with adjuvant anti-PD-1 therapy

Julia Forschner, J. Huynh, Christopher Schroeder, Sorin Armeanu–Ebinger, Olga Kelemen, Axel Gschwind, Irina Bonzheim, Thomas Eigentler, Teresa Amaral, Stephan Ossowski, O. Rieß, L. Flatz, C. Garbe, A. Forschner, Markus Reitmajer   +14 more
openalex   +1 more source

Adjuvant anti-PD-1 therapy improves melanoma-specific survival in stage IIIC-IV melanoma patients with high tumor mutation burden and <i>BRAF V600</i> mutation. [PDF]

Front Oncol
Forschner J, Huynh J, Schroeder C, Armeanu-Ebinger S, Seibel-Kelemen O, Gschwind A, Bonzheim I, Eigentler TK, Amaral T, Ossowski S, Flatz L, Garbe C, Forschner A, Reitmajer M.   +13 more
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Longitudinal ultra-sensitive mutation burden sequencing for precise minimal residual disease assessment in AML. [PDF]

Nat Commun
Wu Y, Zhang S, Feng R, Xiao K, Wang T, Bai J, Zhou X, Wang Y, Dai P, Liu H, Wu LR.   +10 more
europepmc   +1 more source

Prognostic implications of ERLncRNAs in ccRCC: a novel risk score model and its association with tumor mutation burden and immune microenvironment. [PDF]

Discov Oncol
Feng K, Li J, Li J, Li Z, Li Y.
europepmc   +1 more source

Circulating resistin levels and mutation burden of the RETN gene variants predict long-term mortality in a Taiwanese population. [PDF]

Sci Rep
Hsu LA, Teng MS, Wu S, Liao MS, Chou HH, Ko YL.   +5 more
europepmc   +1 more source

A Case of Advanced Extramammary Paget's Disease With a High Tumor Mutation Burden That Showed Partial Lymph Node Regression With Pembrolizumab. [PDF]

Cureus
Horisaki K, Taki T, Mori S, Okumura M, Akiyama M.   +4 more
europepmc   +1 more source

The burden of deleterious mutations shaping fitness variation. Mutation load dynamics and epigenetic mechanisms underlying reproductive success and survival in black grouse (Lyrurus tetrix)

Rebecca Shuhua Chen
openalex   +2 more sources

FAT4 Mutation is Related to Tumor Mutation Burden and Favorable Prognosis in Gastric Cancer. [PDF]

Curr Genomics
Li Q, Chu Y, Yao Y, Song Q.
europepmc   +1 more source