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Clone selection and the mutation rate
Theoretical Population Biology, 1975Abstract A statistical model for mutation and selection is formulated for organisms that reproduce by division. The mutation rate that optimizes the probability of clone survival is approximated using the theory of branching processes. However, it is shown by example that this optimizing mutation rate need not be the most advantageous mutation rate ...
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Spontaneous Mutation Rate in Drosophila
The American Naturalist, 1947The frequency of spontaneously occurring lethal mutations in the X-chromosome of the Sw-b stock of D. melanogaster was found to be higher among spermatozoa of previously unmated males 16 to 17 days, and 32 to 33 days after emergence than among 1- to 2-day old males (Table 1).
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Mutation bias reflects natural selection in Arabidopsis thaliana
Nature, 2022Moises Exposito-Alonso +2 more
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Mutation Rate of the F Episome
Science, 1995F, Taddei, M, Radman, J A, Halliday
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Differential DNA mismatch repair underlies mutation rate variation across the human genome
Nature, 2015Fran Supek, Ben Lehner, Lehner Ben
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Chromatin organization is a major influence on regional mutation rates in human cancer cells
Nature, 2012Ben Lehner +2 more
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Parent–progeny sequencing indicates higher mutation rates in heterozygotes
Nature, 2015Laurence D Hurst, Dacheng Tian
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Genetic drift, selection and the evolution of the mutation rate
Nature Reviews Genetics, 2016Hongan Long +2 more
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