Results 41 to 50 of about 6,858 (298)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Universally Composable RFID Mutual Authentication

IEEE Transactions on Dependable and Secure Computing, 2015
Universally Composable (UC) framework provides the strongest security notion for designing fully trusted cryptographic protocols, and it is very challenging on applying UC security in the design of RFID mutual authentication protocols. In this paper, we formulate the necessary conditions for achieving UC secure RFID mutual authentication protocols ...
Chunhua Su, Bagus Santoso, Yingjiu Li, Robert H. Deng, Xinyi Huang 0001   +4 more
openaire   +3 more sources

RAMHU: A new robust lightweight scheme for mutual users authentication in healthcare applications

, 2019
Providing a mechanism to authenticate users in healthcare applications is an essential security requirement to prevent both external and internal attackers from penetrating patients’ identities and revealing their health data.
Al-Zubaidie, Mishall, Zhang, Zhongwei, Zhang, Ji   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A mutual exclusion key pairing scheme for preserving the privacy of channel shared 5G users

Alexandria Engineering Journal
The fifth generation (5G) network ensures terahertz communication and low latency features to improve the Quality of Service (QoS). Based on the communication and service demands, the security and privacy requirements of the users directly impact the QoS.
Meshari D. Alanazi, Mohammed Albekairi, Turki M. Alanazi, Salwa Othmen, Chahira Lhioui, Ayman Alfahid, Ghulam Abbas, Ahmed Emara   +7 more
doaj   +1 more source

A Mutual Authentication Scheme for Secure Fog Computing Service Handover in Vehicular Network Environment

IEEE Access, 2019
Handover schemes play a vital role on fog computing service (FCS) provided through vehicular network. It not only determines the quality of services (QoSs) but also the security and safety of vehicular network system against adversaries.
Favian Dewanta, Masahiro Mambo
doaj   +1 more source

Quantum direct communication with mutual authentication

Quantum Inf. Comput., 2009
In this paper, we first point out that some recently proposed quantum direct communication (QDC) protocols with authentication are vulnerable under some specific attacks, and the secrete message will leak out to the authenticator who is introduced to authenticate users participating in the communication.
Yen C.-A., Horng S.-J., Goan H.-S., Kao T.-W., Chou Y.-H.   +4 more
openaire   +2 more sources

Criptografía ligera en dispositivos de identificación por radiofrecuencia- RFID [PDF]

, 2008
Esta tesis se centra en el estudio de la tecnología de identificación por radiofrecuencia (RFID), la cual puede ser considerada como una de las tecnologías más prometedoras dentro del área de la computación ubicua.
Peris López, Pedro
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source