Results 61 to 70 of about 45,964 (288)

Inferring the directionality of coupling with conditional mutual information

open access: yesPhysical Review E, 2008
Uncovering the directionality of coupling is a significant step in understanding drive-response relationships in complex systems. In this paper, we discuss a nonparametric method for detecting the directionality of coupling based on the estimation of information theoretic functionals.
Vejmelka, M. (Martin)   +1 more
openaire   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

DOA Estimation Using Fourth-Order Cumulants in Nested Arrays with Structured Imperfections

open access: yesSensors, 2020
Recently developed super nested array families have drawn much attention owing to their merits on keeping the benefits of the standard nested arrays while further mitigating coupling in dense subarray portions.
Baoping Wang, Junhao Zheng
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

DOA Estimation and Tracking of ULAs with Mutual Coupling

open access: yesIEEE Transactions on Aerospace and Electronic Systems, 2012
A class of subspace-based methods for direction-of-arrival (DOA) estimation and tracking in the case of uniform linear arrays (ULAs) with mutual coupling is proposed. By treating the angularly-independent mutual coupling as angularly-dependent complex array gains, the middle subarray is found to have the same complex array gains. Using this property, a
Bin Liao 0001   +2 more
openaire   +3 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Mutual Coupling Effect of Microstrip Antenna Array

open access: yes, 2012
Microstrip patch antenna is widely used due to the advantages such as small size and mass. However, when the patches are close to each other, the mutual coupling can’t be neglected.
Becerra, Darwin R.   +2 more
core   +1 more source

Self-Tuning Synthesis Filter against Mutual Coupling and Interferences for GNSS and Its Implementation on Embedded Board

open access: yesEURASIP Journal on Advances in Signal Processing, 2010
Traditional spatial-temporal adaptive signal processing techniques are often applied to conduct narrowband and wideband interferences. However, its mitigation performance degrades greatly due to mutual coupling.
Chung-Liang Chang
doaj   +2 more sources

Transmission Nonreciprocity in a Mutually Coupled Circulating Structure [PDF]

open access: yesPhysical Review Letters, 2018
6 pages and 4 figures. The resolutions of the figure files are lowered, and the supplementary materials are not included, due to the upload limit imposed by ...
He, Bing   +3 more
openaire   +3 more sources

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