Results 61 to 70 of about 133,329 (294)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Mitigation of Mutual Coupling Effects in Multi-Beam Echosounder Calibration under Near-Field Conditions

Journal of Marine Science and Engineering
The advancement of unmanned platforms is driving the miniaturization and cost reduction of the multi-beam echosounder (MBES). In the process of MBES array calibration, the mutual coupling significantly impacts the performance of parameter estimation.
Wanyuan Zhang, Weijia Yuan, Gongwu Sun, Tengjiao He, Junqi Qu, Chao Xu   +5 more
doaj   +1 more source

Use of Mutual Coupling to Decrease Parasitic Inductance of Shunt Capacitor Filters [PDF]

, 2015
In this paper, we propose and study several new designs of a shunt capacitor filter with two surface-mount technology capacitors. These designs make use of mutual inductance effects to increase the attenuation provided by the filter in the range of high ...
Bernal Méndez, Joaquín, Freire Rosales, Manuel José, Joaquin Bernal Mendez (Coordinador), Sebastián, Ramiro   +3 more
core  

Selectivity as a function of membrane thickness: gas separation and pervaporation [PDF]

, 1994
In this article, the pervaporation selectivity as a function of the membrane thickness is studied for the dehydration of acetic acid. From this study, it appeared that the selectivity of polysulfone (PSF), poly(vinyl chloride) (PVC), and ...
Koops, G.H., Mulder, M.H.V., Nolten, J.A.M., Nolten-Oude Hendrikman, J.A.M., Smolders, C.A., Smolders, C.A.   +5 more
core   +4 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Out-of-Band Mutual Coupling Suppression for Microstrip Antennas Using Characteristic Mode Analysis and Shorting Pins

IEEE Access, 2019
A method combining characteristic mode analysis and shorting pins is presented to reduce out-of-band mutual coupling of linearly polarized rectangular microstrip antennas.
Zhenpeng Ma, Zhao Yang, Qi Wu, Donglin Su   +3 more
doaj   +1 more source

Collective Phase Sensitivity

, 2008
The collective phase response to a macroscopic external perturbation of a population of interacting nonlinear elements exhibiting collective oscillations is formulated for the case of globally-coupled oscillators.
A. T. Winfree, Hiroshi Kori, Hiroya Nakao, Kensuke Arai, S. C. Manrubia, Y. Kuramoto, Yoji Kawamura, Yoshiki Kuramoto   +7 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

EBG Structures for Reduction of Mutual Coupling in Patch Antennas Arrays

Journal of Communications Software and Systems, 2017
An important issue in antenna array design is reduction of mutual coupling. In square microstrip antennas this reduction can be achieved by using electromagnetic band-gap (EBG) structures.
F. Benykhlef, N. Boukli-Hacene
doaj  

Mutual Coupling Reduction for Dual-Band MIMO Antenna with Simple Structure [PDF]

Radioengineering, 2017
In this paper, a novel dual-band MIMO (multi¬ple input, multiple output) antenna for WLAN (wireless local area network) applications is presented. The MIMO antenna contains two dual-band antenna elements, each of which comprises a T-shaped monopole and a
Chao-ming Luo, Jing-song Hong, Muhammad Amin   +2 more
doaj