Results 41 to 50 of about 1,000,824 (299)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Deliberation and Non-Deliberative Communication
Journal of Deliberative Democracy, 2020 The goal of this work is to clarify how certain democratic goods — notably, empowered inclusion and mutual respect — can be both antecedents to and outcomes of successful communication.
Edana Beauvais
doaj +2 more sources
Coexistence and competitive exclusion in mutualism [PDF]
Ecology, 2019 AbstractThe competitive exclusion principle is fundamental to understanding coexistence. Well‐established theories predict the conditions for coexistence in consumer–resource interactions. Given that species often compete for commodities offered by mutualists, competitive exclusion theory should also be critical to understanding how mutualisms function.
Johnson, Christopher A. +1 more
openaire +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Group Mutual Exclusion Based on Priorities
Journal of Computer Science and Technology, 2011 We propose a distributed solution for the group mutual exclusion problem based on priorities, in a network with no share memory whose members only communicate by messages.
Karina M. Cenci, Jorge Raúl Ardenghi
doaj
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Correctness Verification of Mutual Exclusion Algorithms by Model Checking
ModellingMutual exclusion algorithms are at the heart of concurrent/parallel and distributed systems. It is well known that such algorithms are very difficult to analyze, and in the literature, different conjectures about starvation freedom and the number of by ...
Libero Nigro, Franco Cicirelli
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Distributed mutual exclusion algorithms
, 1993 In this thesis we present three original algorithms which solve the distributed mutual exclusion problem. Two of the three solve the problem of allowing only one site at a time into the critical section.
Banta, Paul
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source