Results 41 to 50 of about 485,027 (292)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Formal Modeling and Verification of Lycklama and Hadzilacos’s Mutual Exclusion Algorithm

open access: yesMathematics
This study describes our thorough experience of formal modeling and exhaustive verification of concurrent systems, particularly mutual exclusion algorithms. The experience focuses on Lycklama and Hadzilacos’s (LH) mutual exclusion algorithm.
Libero Nigro
doaj   +1 more source

Design of a Mutual Exclusion and Deadlock Algorithm in PCBSD – FreeBSD

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2014
This paper shows the implementation of mutual exclusion in PCBSD-FreeBSD operating systems on SMPng environments, providing solutions to problems like investment priority, priority propagation, interlock, CPU downtime, deadlocks, between other.
Libertad Caicedo Acosta   +3 more
doaj   +1 more source

Comment on "Statistical Distribution for Generalized Ideal Gas of Fractional-Statistics Particles", Phys. Rev. Lett. {\bf 73}, 922 (1994)

open access: yes, 2009
In Phys. Rev. Lett. 67, 937 (1991) [1], Haldane introduced the fruitful concept of fractional exclusion statistics (FES). One of the most influential papers in which the thermodynamics of FES systems was deduced is Y.-S. Wu, Phys. Rev. Lett.
Anghel, Dragoş-Victor
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Deliberation and Non-Deliberative Communication

open access: yesJournal of Deliberative Democracy, 2020
The goal of this work is to clarify how certain democratic goods — notably, empowered inclusion and mutual respect — can be both antecedents to and outcomes of successful communication.
Edana Beauvais
doaj   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Self-stabilizing K-out-of-L exclusion on tree network [PDF]

open access: yes, 2008
In this paper, we address the problem of K-out-of-L exclusion, a generalization of the mutual exclusion problem, in which there are $\ell$ units of a shared resource, and any process can request up to $\mathtt k$ units ($1\leq\mathtt k\leq\ell$).
Datta, Ajoy K.   +3 more
core   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Modeling and Analysis of Dekker-Based Mutual Exclusion Algorithms

open access: yesComputers
Mutual exclusion is a fundamental problem in concurrent/parallel/distributed systems. The first pure-software solution to this problem for two processes, which is not based on hardware instructions like test-and-set, was proposed in 1965 by Th.J.
Libero Nigro   +2 more
doaj   +1 more source

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