Results 51 to 60 of about 485,027 (292)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Group Mutual Exclusion Based on Priorities
Journal of Computer Science and Technology, 2011 We propose a distributed solution for the group mutual exclusion problem based on priorities, in a network with no share memory whose members only communicate by messages.
Karina M. Cenci, Jorge Raúl Ardenghi
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular motor traffic in a half-open tube
, 2005 The traffic of molecular motors which interact through mutual exclusion is studied theoretically for half-open tube-like compartments. These half-open tubes mimic the shapes of axons.
Ajdari A +9 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Correctness Verification of Mutual Exclusion Algorithms by Model Checking
ModellingMutual exclusion algorithms are at the heart of concurrent/parallel and distributed systems. It is well known that such algorithms are very difficult to analyze, and in the literature, different conjectures about starvation freedom and the number of by ...
Libero Nigro, Franco Cicirelli
doaj +1 more source
Erythroleukemia: Classification
eJHaem, 2023 Acute erythroid leukemia (AEL) is a rare (2%–5%) form of acute myeloid leukemia (AML). Molecular alterations found in AEL resemble those of other AMLs. We report a classification of AELs in three major classes, with different prognosis and some specific ...
Nathalie Cervera +8 more
doaj +1 more source
Mutual Exclusion Verification of Parameterized Reader-Writer Algorithm: a Case Study [PDF]
, 2006 This paper presents the verification of mutual-exclusion properties of parameterized reader-writer algorithm. A class of diagram called Predicate diagrams [1] is used for representing the abstractions of parameterized systems described by specifications ...
Nugraheni, C. E. (Cecilia)
core
Hydrodynamic limit of a disordered lattice gas
, 2003 We consider a model of lattice gas dynamics in the d-dimensional cubic lattice in the presence of disorder. If the particle interaction is only mutual exclusion and if the disorder field is given by i.i.d.
Faggionato, A., Martinelli, F.
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source