Results 91 to 100 of about 15,770,233 (254)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Uncertainty relation for mutual information [PDF]

Physical Review A, 2014
6 pages, 2 ...
Schneeloch, James, Broadbent, Curtis J., Howell, John C.   +2 more
openaire   +3 more sources

Sequence alignment, mutual information, and dissimilarity measures for constructing phylogenies [PDF]

, 2011
Background: Existing sequence alignment algorithms use heuristic scoring schemes based on biological expertise, which cannot be used as objective distance metrics.
Penner, Orion, Grassberger, Peter, Maya Paczuski, Paczuski Maya, Peter Grassberger, Orion Penner, Penner Orion, Grassberger Peter, Paczuski, Maya   +8 more
core   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Physical layer DVB-SH performance prediction based on mutual information [PDF]

, 2012
Digital Video Broadcasting-Satellite Handled (DVB-SH) is a hybrid satellite terrestrial broadcasting standard dedicated to provide video or audio services for handheld terminals.
Chauvet, Wilfried, Amiot-Bazile, Caroline, J. Lacan, B. Ros, Lacan, Jérôme, F. Lacoste, C. Amiot‐Bazile, Lacoste, Frédéric, Ros, Benjamin, W. Chauvet   +9 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Role of mutual information in entropy production under information exchanges

New Journal of Physics, 2013
We relate the information exchange between two stochastic systems to the nonequilibrium entropy production in the whole system. By deriving a general formula that decomposes the total entropy production into the thermodynamic and informational parts, we ...
Takahiro Sagawa, Masahito Ueda
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Boundary mutual information in double holography

Journal of High Energy Physics
We consider a composite system where AdS3 gravity is coupled to a flat heat bath and investigate the mutual information between two subregions on the intersection of the AdS3 and bath, referred to as the boundary mutual information (BMI).
Yuxuan Liu, Yi Ling, Zhuo-Yu Xian
doaj   +1 more source

On Dynamical Measures of Quantum Information

Entropy
In this work, we use the theory of quantum states over time to define joint entropy for timelike-separated quantum systems. For timelike-separated systems that admit a dual description as being spacelike-separated, our notion of entropy recovers the ...
James Fullwood, Arthur J. Parzygnat
doaj   +1 more source