Results 71 to 80 of about 1,885,677 (275)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

On universal terms of holographic entanglement entropy in theories with hyperscaling violation

open access: yes, 2018
We examine the holographic entanglement entropy in hyperscaling violating backgrounds. Precisely in such theories by semi-analytic computation, we use holographic methods to derive the universal terms of entanglement entropy in various dimensions.
Tanhayi, Mohammad Reza
core   +1 more source

Dictator functions maximize mutual information [PDF]

open access: yesThe Annals of Applied Probability, 2018
accepted for publication in the Annals of Applied Probability; 8 pages, 1 ...
Georg, Pichler   +2 more
openaire   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Mutual information in the Tangled Nature Model [PDF]

open access: yes, 2009
We consider the concept of mutual information in ecological networks, and use this idea to analyse the Tangled Nature model of co-evolution. We show that this measure of correlation has two distinct behaviours depending on how we define the network in ...
Jensen, Henrik Jeldtoft   +2 more
core  

Mutual Information-Based Visual Servoing [PDF]

open access: yesIEEE Transactions on Robotics, 2011
In this work we propose a new information theoretic approach to achieve visual servoing directly utilizing the information (as defined by Shannon) contained in the images. A metric derived from information theory, mutual information, is considered. Mutual information is widely used in multi-modal image registration since it is insensitive to changes in
Dame, Amaury, Marchand, Eric
openaire   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Role of mutual information in entropy production under information exchanges

open access: yesNew Journal of Physics, 2013
We relate the information exchange between two stochastic systems to the nonequilibrium entropy production in the whole system. By deriving a general formula that decomposes the total entropy production into the thermodynamic and informational parts, we ...
Takahiro Sagawa, Masahito Ueda
doaj   +1 more source

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