Results 61 to 70 of about 15,770,233 (254)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Tsallis Mutual Information for Document Classification
Entropy, 2011 Mutual information is one of the mostly used measures for evaluating image similarity. In this paper, we investigate the application of three different Tsallis-based generalizations of mutual information to analyze the similarity between scanned ...
Màrius Vila +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Distribution of Mutual Information [PDF]
, 2002 The mutual information of two random variables i and j with joint probabilities t_ij is commonly used in learning Bayesian nets as well as in many other fields. The chances t_ij are usually estimated by the empirical sampling frequency n_ij/n leading to a point estimate I(n_ij/n) for the mutual information.
openaire +4 more sources
On Finite-Time Mutual Information
2022 IEEE International Symposium on Information Theory (ISIT), 2022 Shannon-Hartley theorem can accurately calculate the channel capacity when the signal observation time is infinite. However, the calculation of finite-time mutual information, which remains unknown, is essential for guiding the design of practical communication systems.
Jieao Zhu +3 more
openaire +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Mutual information for the detection of crush. [PDF]
PLoS ONE, 2011 Fatal crush conditions occur in crowds with tragic frequency. Event organizers and architects are often criticised for failing to consider the causes and implications of crush, but the reality is that both the prediction and prevention of such conditions
Peter Harding, Steve Gwynne, Martyn Amos
doaj +1 more source
A mutual information kernel for sequences [PDF]
2004 IEEE International Joint Conference on Neural Networks (IEEE Cat. No.04CH37541), 2005 We propose a new kernel for strings which borrows ideas and techniques from information theory and data compression. This kernel can be used in combination with any kernel method, in particular support vector machines for protein classification.
Marco Cuturi, Jean-Philippe Vert
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Quantum mutual information in time
New Journal of PhysicsWhile the quantum mutual information is a fundamental measure of quantum information, it is only defined for spacelike separated quantum systems. Such a limitation is not present in the theory of classical information, where the mutual information ...
Zhen Wu +3 more
doaj +1 more source