Results 61 to 70 of about 1,885,677 (275)

Weighted Mutual Information for Aggregated Kernel Clustering

open access: yesEntropy, 2020
Background: A common task in machine learning is clustering data into different groups based on similarities. Clustering methods can be divided in two groups: linear and nonlinear. A commonly used linear clustering method is K-means.
Nezamoddin N. Kachouie, Meshal Shutaywi
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Space-time generalization of mutual information

open access: yesJournal of High Energy Physics
The mutual information characterizes correlations between spatially separated regions of a system. Yet, in experiments we often measure dynamical correlations, which involve probing operators that are also separated in time.
Paolo Glorioso   +2 more
doaj   +1 more source

Machine Learning with Squared-Loss Mutual Information

open access: yesEntropy, 2012
Mutual information (MI) is useful for detecting statistical independence between random variables, and it has been successfully applied to solving various machine learning problems.
Masashi Sugiyama
doaj   +1 more source

Derivative of BICM mutual information [PDF]

open access: yesElectronics Letters, 2007
submitted to the IET Electronics Letters.
Fabregas, Albert Guillen I   +1 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Improved Neural Networks Based on Mutual Information via Information Geometry

open access: yesAlgorithms, 2019
This paper presents a new algorithm based on the theory of mutual information and information geometry. This algorithm places emphasis on adaptive mutual information estimation and maximum likelihood estimation.
Meng Wang   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

On Triple Mutual Information

open access: yesAdvances in Applied Mathematics, 1995
The mutual information of two random variables plays fundamental roles in many areas of applied mathematics. This quantity can be generalized to finite sets of random variables. In contrast to the nonnegativity of the usual mutual information, the triple mutual information can be negative as well as positive and its sign gives us a rough indication of ...
openaire   +3 more sources

Hierarchical clustering using mutual information [PDF]

open access: yesEurophysics Letters (EPL), 2005
We present a method for hierarchical clustering of data called {\it mutual information clustering} (MIC) algorithm. It uses mutual information (MI) as a similarity measure and exploits its grouping property: The MI between three objects $X, Y,$ and $Z$ is equal to the sum of the MI between $X$ and $Y$, plus the MI between $Z$ and the combined object ...
Kraskov, A.   +3 more
openaire   +4 more sources

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