Results 111 to 120 of about 657,350 (280)
Análisis transcripcional de la región genética RvD1 de Mycobacterium bovis
Mycobacterium bovis comparte una identidad del 99,9% con los genomas de M. tuberculosis, M. africanum y M. microti. Dentro del 0,1% de esta diferencia se encuentran dos regiones genéticas propias de M.
Víctor Manuel Tibatá R. +3 more
doaj
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
La mutevolezza del periodo di imposta-mv dell’imposta liquida sul reddito-mv
Il contributo analizza il tema del periodo d’imposta nella teoria dell’imposta liquida di Marco Versiglioni, evidenziando come la capacità contributiva dei contribuenti sia mutevole nel tempo e richieda strumenti fiscali più flessibili rispetto alla ...
Francesco Vincenzo Albertini
core +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
La responsabilidad del transportista en caso de accidente en transporte ferroviario
El trabajo analiza el régimen de responsabilidad en caso de accidente en transporte ferroviario contenido en las RU CIV; su incorporación en la UE mediante el Reglamento (CE) no 1371/2007; y la adaptación e interpretación de dichas normas en los ...
Petit Laval, MV, Rosafio, E
core +1 more source
Reddito liquido-mv, Liquid income qualified accounts-mv e residenza fiscale
L’analisi sul concetto di Reddito liquido-mv si basa sull’applicazione del “ragionamento matematico” al diritto tributario. L’approccio “matematico” potrebbe legittimare il ricorso a modelli impositivi che prevedono l’assoggettamento dei redditi ad ...
Pietro Selicato
core

