Results 1 to 10 of about 1,584,070 (132)

Mitophagy in carcinogenesis and cancer treatment

open access: yesDiscover Oncology, 2021
In order to maintain a functional mitochondrial network, cells have developed a quality control mechanism, namely mitophagy. This process can be induced through different pathways.
Tatiana V. Denisenko   +2 more
doaj   +1 more source

Simple and Efficient Protocol for Subcellular Fractionation of Normal and Apoptotic Cells

open access: yesCells, 2021
Subcellular fractionation approaches remain an indispensable tool among a large number of biochemical methods to facilitate the study of specific intracellular events and characterization of protein functions.
Viacheslav V. Senichkin   +3 more
doaj   +1 more source

Drug toxicity assessment: cell proliferation versus cell death

open access: yesCell Death Discovery, 2022
Analysis of the toxicity of chemotherapeutic drugs is one of the main tasks of clinical pharmacology. Decreased viability of tumor cells may reflect two important physiological processes, namely the arrest of proliferation associated with disturbances in
Elena V. Sazonova   +3 more
doaj   +1 more source

Measles virus glycoprotein-based lentiviral targeting vectors that avoid neutralizing antibodies [PDF]

open access: yes, 2012
Lentiviral vectors (LVs) are potent gene transfer vehicles frequently applied in research and recently also in clinical trials. Retargeting LV entry to cell types of interest is a key issue to improve gene transfer safety and efficacy.
Abel, Tobias   +5 more
core   +6 more sources

Conserved quantities in STEGR and applications

open access: yesEuropean Physical Journal C: Particles and Fields, 2023
We derive conservation laws in Symmetric Teleparallel Equivalent of General Relativity (STEGR) with direct application of Noether’s theorem. This approach allows us to construct covariant conserved currents, corresponding superpotentials and invariant ...
E. D. Emtsova   +2 more
doaj   +1 more source

Platinum drugs and taxanes: can we overcome resistance?

open access: yesCell Death Discovery, 2021
Cancer therapy is aimed at the elimination of tumor cells and acts via the cessation of cell proliferation and induction of cell death. Many research publications discussing the mechanisms of anticancer drugs use the terms “cell death” and “apoptosis ...
Elena V. Sazonova   +3 more
doaj   +1 more source

Effective Removal of Cationic Dyes from Aqueous Solutions by Using Black Cumin (Nigella sativa) Seed Pulp and Biochar

open access: yesBioResources, 2023
Black cumin seed pulp (C), as well as biochar (CC) produced via pyrolysis of black cumin seed pulp were used to remove methylene violet 2B (MV) and basic yellow 28 (BY28) from aqueous solution.
Sedef Sismanoglu   +3 more
doaj   +2 more sources

Na,K-ATPase as a target for endogenous cardiotonic steroids: What's the evidence?

open access: yesGenes and Diseases, 2021
With an exception of few reports, the plasma concentration of ouabain and marinobufagenin, mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less than 1 nM. During the last 3 decades, the implication of these endogenous CTS
Sergei N. Orlov   +6 more
doaj   +1 more source

Prognostic signature based on mitochondria quality control proteins for the prediction of lung adenocarcinoma patients survival

open access: yesCell Death Discovery, 2023
Lung cancer is the leading cause of cancer mortality worldwide. In recent years, the incidence of lung cancer subtype lung adenocarcinoma (LUAD) has steadily increased.
Anna S. Gorbunova   +7 more
doaj   +1 more source

Volumetric Сapnography As a Tool for Evaluation of Alveolar Ventilation Effectiveness in Clinical Practice

open access: yesОбщая реаниматология, 2018
The purpose of the study was to compare the relationship between the dead space volume and tidal volume (VD/VT) using volumetric capnography (VCap) during pressure controlled (PCV) and pressure supported (PSV) ventilation mode in the postoperative period.
P. Török   +10 more
doaj   +1 more source

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