Results 101 to 110 of about 1,577,706 (298)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sécurité des applications AJAX: Unity Web SARL [PDF]
, 2008 AJAX est un ensemble de technologies Internet déjà existantes depuis quelques années et remises au goût du jour il y a peu. Elles permettent de créer des flux de communication entre client et serveur de manière asynchrone.
Hauri, Rolf, Koker, Cem
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Ciência Animal Brasileira, 2009 Os tumores orais em cães representam cerca de 6% de todas as neoplasias dessa espécie. O objetivo deste trabalho foi realizar um estudo epidemiológico dos cães com tumores orais atendidos no Hospital de Clínicas Veterinárias da Universidade Federal do ...
Cristiano Gomes +7 more
doaj +1 more source
Journal of Mathematical Analysis and Applications, 1999 The aim of this paper is to go deeper into the questions of MV-algebras provided with square roots. Höhle proposed a classification of MV-algebras with square roots, introducing the strict MV-algebras and proving that every MV-algebra with square roots is exactly a Boolean algebra, or a strict algebra, or isomorphic to the product of both. Due to their
openaire +2 more sources
International Journal of Approximate Reasoning, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
DI NOLA, Antonio +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Prevalence survey of musculoskeletal and connective tissue disorders in the Russian Federation
Фармакоэкономика, 2019 Diseases of the musculoskeletal system and connective tissues are becoming more and more common. As these disorders are associated with temporary or permanent disability as well as a costly treatment, this socially-significant issue requires close ...
T. A. Oleynikova +2 more
doaj +1 more source
Agricultural Technology Adoption and Land Productivity: Evidence from the Rice-Prawn Gher Farming System in Bangladesh [PDF]
Rice-prawn gher (RPG) farming system is an indigenous agricultural technology solely developed by farmers since mid 1980s. The present study aims to estimate the land productivity of modern varieties (MV) paddy production under RPG and (year-round modern
Barmon, Basanta Kumar +2 more
core +1 more source