Results 91 to 100 of about 218,624 (251)

Coupling an MV-algebra with a Boolean algebra

open access: yesInternational Journal of Approximate Reasoning, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Costas A. Drossos, Panagis Karazeris
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Image acquisition of velocity encoded (VENC) cine cardiovascular magnetic resonance imaging (CMR) at the level of mitral valve (MV)

open access: yes, 2011
A) Cine 4 chamber image demonstrating the prescription of slice at the level of the tips of the MV leaflets. B) VENC CMR short axis image at the level of MV leaflet tips.
Craig Truman (51618)   +7 more
core   +1 more source

State morphism MV-algebras

open access: yesInternational Journal of Approximate Reasoning, 2011
We present a complete characterization of subdirectly irreducible MV-algebras with internal states (SMV-algebras). This allows us to classify subdirectly irreducible state morphism MV-algebras (SMMV-algebras) and describe single generators of the variety of SMMV-algebras, and show that we have a continuum of varieties of SMMV-algebras.
Anatolij Dvurecenskij   +2 more
openaire   +4 more sources

On The Spectrum of Countable MV-algebras.

open access: yesTFSS, 2023
‎In this paper we consider MV-algebras and their prime spectrum‎. ‎We show that there is an uncountable MV-algebra that has the same spectrum as the free MV-algebra over one element‎, ‎that is‎, ‎the MV-algebra $Free_1$ of McNaughton functions from $[0,1]$ to $[0,1]$‎, ‎the continuous‎, ‎piecewise linear functions with integer coefficients‎.
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Prevalence survey of musculoskeletal and connective tissue disorders in the Russian Federation

open access: yesФармакоэкономика, 2019
Diseases of the musculoskeletal system and connective tissues are becoming more and more common. As these disorders are associated with temporary or permanent disability as well as a costly treatment, this socially-significant issue requires close ...
T. A. Oleynikova   +2 more
doaj   +1 more source

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