Results 71 to 80 of about 1,577,706 (298)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Role of the Mass Collaboration in the Development of Society, Business and the State
Интеллект. Инновации. Инвестиции, 2019 The relevance of the topic under consideration is due to the growing popularity of the mass collaboration as a tool for activating the collective mind in order to increase the effectiveness of the organization’s activities and economic development ...
Yu.M. Polyakova
doaj +1 more source
RR Lyrae-based calibration of the Globular Cluster Luminosity Function
, 2005 We test whether the peak absolute magnitude Mv(TO) of the Globular Cluster Luminosity Function (GCLF) can be used for reliable extragalactic distance determinations. Starting with the luminosity function of the Galactic Globular Clusters listed in Harris
Ashman +59 more
core +2 more sources
From Crepes to Pancakes in the MV Model [PDF]
, 2000 The McLerran-Venugopalan model provides a framework which allows one to compute the gluon distribution function of a very large nucleus from the equations of QCD, provided that the longitudinal momentum fraction, xF, is sufficiently small.
Mahlon, Gregory
core +2 more sources
Lexicographic pseudo MV-algebras
Journal of Applied Logic, 2015 A lexicographic pseudo MV-algebra is an algebra that is isomorphic to an interval in the lexicographic product of a linear unital group with an arbitrary $\ell$-group. We present conditions when a pseudo MV-algebra is lexicographic. We show that a key condition is the existence of a lexicographic ideal, or equivalently, a case when the algebra can be ...
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A coupled mitral valve -- left ventricle model with fluid-structure interaction
, 2017 Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX +11 more
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Mass and angular momentum for the Kerr black hole in TEGR and STEGR
European Physical Journal C: Particles and FieldsWe study the energy–momentum characteristics of the rotating black hole–Kerr solution of general relativity in the teleparallel equivalent of general relativity (TEGR) and the symmetric teleparallel equivalent of general relativity (STEGR).
E. D. Emtsova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source