CD20 and CD19 targeted vectors induce minimal activation of resting B lymphocytes [PDF]
B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
A Pezzutto +51 more
core +6 more sources
Multiple Sclerosis Lesions Segmentation Using Attention-Based CNNs in FLAIR Images
Objective: Multiple Sclerosis (MS) is an autoimmune and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI).
Mehdi Sadeghibakhi +2 more
doaj +1 more source
A Solid State Transformer model for power flow calculations [PDF]
This paper presents the implementation of a Solid State Transformer (SST) model in OpenDSS. The goal is to develop a SST model that could be useful for assessing the impact that the replacement of the conventional iron-and-copper transformer with the SST
Guerra Sánchez, Luis Gerardo +1 more
core +2 more sources
Semitopological BL-Algebras and MV -Algebras
Abstract In this paper, by considering the notion of upsets, for any element x of a BL-algebra L, we construct a topology Tx on L and show that L-algebras with this topology formes a semitopological BL-algebras. Then we obtain some of the topological aspects of this structure such as connectivity and compactness. Moreover, we introduced
Zahiri O., Borzooei R. A.
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A matter of new life and cell death: programmed cell death in the mammalian ovary
Background The mammalian ovary is a unique organ that displays a distinctive feature of cyclic changes throughout the entire reproductive period. The estrous/menstrual cycles are associated with drastic functional and morphological rearrangements of ...
Mikhail S. Chesnokov +3 more
doaj +1 more source
Physical Activity Minimum Threshold Predicting Improved Function in Adults With Lower‐Extremity Symptoms [PDF]
Objective To identify an evidence‐based minimum physical activity threshold to predict improved or sustained high function for adults with lower‐extremity joint symptoms.
Ainsworth, Barbara +9 more
core +1 more source
Temperature compensated tactile sensing using MOSFET with P(VDF-TrFE)/BaTiO3 capacitor as extended gate [PDF]
This work presents Poly(vinylidene fluoride – trifluoroethylene))/Barium Titanate (P(VDF-TrFE)-BT) nanocomposite based touch sensors tightly coupled with MOSFET devices in extended gate configuration.
Dahiya, Ravinder +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Epidemiology and risk factors for phantom limb pain
Approximately 356 million limb amputations are performed globally every year. In 2005, the prevalence of limb loss in the United States was 1.6 million people; and it is estimated to increase to 3.6 million by 2050.
Shoji Ishigami +2 more
doaj +1 more source

