Results 41 to 50 of about 41,693 (234)

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

open access: yesAdvanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang   +19 more
wiley   +1 more source

Influence of Top Electrode Metal on Resistive Switching in Multilayer MOCVD MoS2 Memristors

open access: yesAdvanced Electronic Materials, EarlyView.
MoS2 memristors typically use evaporated noble metal electrodes. This study compares Pd, Ni, and Al electrodes and sputtered versus evaporated deposition. Pd is passive, while Ni damages MoS2, yielding poor switching. Sputtered Al enables reproducible ECM‐type switching with 95% yield, whereas evaporated Al forms an interfacial oxide that suppresses ...
Dennis Braun   +15 more
wiley   +1 more source

A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk   +6 more
wiley   +1 more source

PbAT: A user‐friendly R/Shiny platform for data‐driven decision support in crop improvement

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Modern plant breeding requires robust analysis of complex, multi‐environment datasets to identify superior genotypes. Although R offers powerful statistical packages, their use often requires programming expertise. Existing graphical user interface (GUI)‐based tools are either limited in scope or not openly accessible, leaving breeders
Krishnan P. Abhijith   +6 more
wiley   +1 more source

Bridging the Python Training Gap for Bioscientists in Brazil: Improvements and Challenges

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT The rapid evolution of high‐throughput technologies in biosciences generates vast and diverse datasets, demanding that bioscientists develop advanced data manipulation and analysis skills. Python, with its versatility and powerful libraries, has become a crucial tool for managing these datasets.
Gustavo Schiavone Crestana   +12 more
wiley   +1 more source

Exploring the Financial Perspective in Sustainability Strategies: The Case of the Tourism Industry

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines the relationship between sustainability and corporate financial performance in the tourism sector. To address the mixed and inconclusive evidence in prior research, we develop an integrated theoretical framework that combines stakeholder theory, the resource‐based view, legitimacy theory, and agency theory and distinguishes
Rebecca Levy Orelli   +3 more
wiley   +1 more source

Experience of using autologous cornea for deep and penetrating keratoplasty in dogs and cats [PDF]

open access: yesBIO Web of Conferences
This paper presents a generalized experience in the treatment of deep corneal ulcers, descemetoceles and perforated corneal ulcers in which keratoplasty was used using autologous cornea.
Saroyan Sergey   +2 more
doaj   +1 more source

FEED ADDITIVE BIOACTIVE KERATIN: QUALITY ASSESSMENT AND FUNCTIONAL PROPERTIES

open access: yesВетеринарная патология, 2021
The article presents the results of studying the feed additive Bioactive Keratin in terms of some quality and safety indicators. When assessing the quality of Bioactive Keratin, it was found that the feed additive is a molecularly dispersed substance of ...
K. V. Esepenok, A. I. Sapozhnikova
doaj   +1 more source

Integrated numerical simulation and source‐sink matching methodology for Basin‐Wide CO2 storage assessment in depleted reservoirs: A Cambay Basin case study

open access: yesDeep Underground Science and Engineering, EarlyView.
This study presents an integrated workflow to evaluate secure and large‐scale CO2 storage in depleted oil reservoirs of the Cambay Basin, India. Industrial CO2 sources are systematically matched with mature oil fields using a quantitative source–sink framework to minimize transport distance and cost.
Bhaskarjyoti Khanikar
wiley   +1 more source

Effects of LED Light Exposure on Lutein and Bioactive Compounds in Nasturtium Flowers (Tropaeolum majus L.)

open access: yesFuture Postharvest and Food, EarlyView.
Red LED supplementation during cultivation modulated the accumulation of bioactive compounds in Tropaeolum majus flowers. Moderate exposure (3–5 h) enhanced antioxidant capacity and increased carotenoids, phenolics, and anthocyanins depending on petal color, highlighting a simple strategy to improve the functional value of edible flowers. ABSTRACT This
Amanda Lais Alves Almeida Nascimento   +8 more
wiley   +1 more source

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