Results 21 to 30 of about 23,529 (262)

Synthesis of Cyclopropene‐Modified Fatty Acids Allows Single‐Cell Quantification of Uptake by Immune Cells

open access: yesAngewandte Chemie, EarlyView.
Cyclopropene fatty acids have been made that allow the study of fatty acid uptake in complex mixtures of immune cells with single cell resolution and combined with metabolic and proteomic analysis so that for the first time nutrient uptake can be correlated to the phenotype of single immune cell.
Luuk Reinalda   +14 more
wiley   +2 more sources

Lev Evgenevich Shaposhnikov in the context of russian philosophy

open access: yesВестник Мининского университета, 2019
Introduction: the present paper aims to portray Lev Shaposhnikov, a Russian scholar, professor, doctor of philosophy as an advocator of the historico-philosophical approach.
A. F. Zamaleev   +7 more
doaj   +1 more source

Microvascular dysfunction: Determinants and treatment, with a focus on hyperglycemia

open access: yesEndocrine and Metabolic Science, 2021
Individuals with prediabetes or type 2 diabetes have an increased risk of diseases that are partly or entirely of microvascular origin (e.g. (lacunar) stroke, depression, cognitive decline, retinopathy, heart failure, chronic kidney disease, and ...
Alfons J.H.M. Houben   +1 more
doaj   +1 more source

Examples of eyes with microvasculature dropout (Mvd) inside the optic disc (Mvd-D), pseudo-Mvd-D, and no Mvd-D.

open access: yes, 2018
A, The Mvd-D and Mvd in the parapapillary region (Mvd-P) are enclosed by yellow and aqua border, respectively. A3, Anterior lamina cribrosa (LC) surface is well visualized as shown by yellow dotted line.
Adeleh Yarmohammadi (5608025)   +8 more
core   +1 more source

Assessing the Environmental Consequences of the Generation and Alteration of Mafic Volcaniclastic Deposits During Large Igneous Province Emplacement

open access: yesGeophysical Monograph Series, Page 117-131., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Benjamin Black   +4 more
wiley  

+1 more source

Disparities in Mitral Valve Disease Associated with Heart Failure

open access: yesReviews in Cardiovascular Medicine
Heart failure (HF) affects millions of people around the world and is a prevalent health issue in the United States. In many cases, HF has an intricate connection with mitral valvular disease (MVD), which can alter a patient’s disease course.
Olivia Foley   +7 more
doaj   +1 more source

Survival differences stratified by low MVD and high MVD in patients with or without BRF2 overexpression.

open access: yes, 2014
Survival differences stratified by low MVD and high MVD in patients with or without BRF2 overexpression.
Lei Qi (173882)   +8 more
core   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

open access: yesAdvanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther   +13 more
wiley   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An   +8 more
wiley   +1 more source

Angiogenesis and Minimal Residual Disease in Patients with Acute Myeloid Leukemia

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2020
Background: Acute myeloid leukemia (AML) is the most prevalent acute leukemia in adults. Bone marrow angiogenesis is crucial for pathogenesis of leukemia, and increasing bone marrow Mean Vascular Density (MVD) and level of angiogenesis factors are seen ...
Pardis Nematollahi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy