Results 31 to 40 of about 23,529 (262)

Evaluation of quantitative muscle MRI and an intelligent phenotyping housing system as advanced phenotyping methods in a mouse model of calpain 3‐deficient muscular dystrophy

Animal Models and Experimental Medicine, EarlyView.
We applied quantitative MRI of the lower limb and automated home‐cage phenotyping to a mouse model of calpainopathy to detect early disease changes. At 15 months, calpain 3‐deficient mice showed increased water T2 values correlating with immune cell infiltration in the soleus and gastrocnemius muscles, while assessment of motor activity revealed only ...
Nicolina Südkamp, Marlena Rohm, Gabriele Russo, Xavier Helluy, Abdulhadi Kocabas, Martijn Froeling, Felix Kleefeld, Denise Manahan‐Vaughan, Tobias Ruck, Frank Jacobsen, Matthias Vorgerd, Johannes Forsting, Lara Schlaffke   +12 more
wiley   +1 more source

Does CD34 Staining Reflect the Angiogenic Process in the Bone Marrow? An Analysis of a Series of Chronic Myeloid Leukemia Patients [PDF]

Journal of Clinical and Diagnostic Research, 2014
Backgorund: Angiogenesis is associated with growth, dissemination and metastasis of tumours. Measurement of Microvascular Density (MVD) is a quantitative method of assessment of angiogenesis and would give a proportional co relate of the angiogenic ...
Krishnan Kulumani Mahadevan, Debdatta Basu, Swarup Kumar   +2 more
doaj   +1 more source

Representative cases of eyes with microvasculature dropout (Mvd) inside the optic disc (Mvd-D).

, 2018
A―G, Left eye of a 74-year-old man with primary open-angle glaucoma (POAG). A, Neuroretinal rim thinning is observed at the temporal area of the optic disc. B, Humphrey Visual Field Analyzer with the 24–2 Swedish interactive threshold algorithm standard (
Adeleh Yarmohammadi (5608025), Min Hee Suh (5608022), Luke J. Saunders (510359), Patricia Isabel C. Manalastas (5608028), Robert N. Weinreb (170002), Tadamichi Akagi (655602), Rafaella C. Penteado (5608031), Linda M. Zangwill (471654), Takuhei Shoji (631378)   +8 more
core   +1 more source

Alcohol consumption and microvascular dysfunction: a J-shaped association: The Maastricht Study

Cardiovascular Diabetology, 2023
Background Microvascular dysfunction (MVD) is an important contributor to major clinical disease such as stroke, dementia, depression, retinopathy, and chronic kidney disease. Alcohol consumption may be a determinant of MVD.
Frank C. T. van der Heide, Simone J. P. M. Eussen, Alfons J. H. M. Houben, Ronald M. A. Henry, Abraham A. Kroon, Carla J. H. van der Kallen, Pieter C. Dagnelie, Martien C. J. M. van Dongen, Tos T. J. M. Berendschot, Jan S. A. G. Schouten, Carroll A. B. Webers, Marleen M. J. van Greevenbroek, Anke Wesselius, Casper G. Schalkwijk, Annemarie Koster, Jacobus F. A. Jansen, Walter H. Backes, Joline W. J. Beulens, Coen D. A. Stehouwer   +18 more
doaj   +1 more source

Clinical Characteristics and Short-Term Outcomes of Patients Presenting with Acute Myocardial Infarction having Multi-vessel disease - A Single Middle- eastern Tertiary-Care Center Experience

Indian Heart Journal, 2022
Objective: Patients with multi-vessel coronary artery disease (MVD) compared to single-vessel coronary artery disease (CAD) have more comorbidities and poor in-hospital outcomes.
Sheeren Khaled, Najeeb Jaha, Ghada Shalaby   +2 more
doaj   +1 more source

MVD analyses.

, 2014
Control group (a), micro-vessel density (MVD) from the 1st day to the 1st week (b, c, d, e ...
Lun Wu (522881), Shengwei Li (522886), Shiji Zhou (522882), Zhengrong Qiao (522885), Zhihao Fu (463189), Jianping Gong (522883), Chang An Liu (522884)   +6 more
core   +1 more source

Male reproductive system in stenopodidean shrimps: Unveiling basal reproductive traits in shrimp‐like Pleocyemata (Stenopodidae and Spongicolidae)

The Anatomical Record, EarlyView.
Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira, Lucas Rezende Penido Paschoal, Fernando José Zara   +2 more
wiley   +1 more source

Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases

Brazilian Journal of Medical and Biological Research, 1997
Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
M.A.S. Medeiros, M.S.F. França, G. Boileau, L. Juliano, K.M. Carvalho   +4 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Plasma Lipidomic Patterns in Patients with Symptomatic Coronary Microvascular Dysfunction

Metabolites, 2021
Coronary microvascular dysfunction (MVD) is a syndrome of abnormal regulation of vascular tone, particularly during increased metabolic demand. While there are several risk factors for MVD, some of which are similar to those for coronary artery disease ...
Jonathan R. Lindner, Brian P. Davidson, Zifeng Song, Claudia S. Maier, Jessica Minnier, Jan Frederick Stevens, Maros Ferencik, Sahar Taqui, J. Todd Belcik, Federico Moccetti, Michael Layoun, Paul Spellman, Mitchell S. Turker, Hagai Tavori, Sergio Fazio, Jacob Raber, Gerd Bobe   +16 more
doaj   +1 more source