Results 121 to 130 of about 51,637 (256)

The Creation of a Weight of Evidence Scoring Database for Risk Factors for Adverse Impacts to Birth Outcomes Using Expert Elicitation

open access: yesBirth Defects Research, Volume 118, Issue 1, January 2026.
ABSTRACT Background Adverse birth outcomes are important public health measures and account for a substantial public health burden. There is considerable diversity of these health endpoints, as well as in the many factors suspected or recognized to increase their risk.
Paul J. Villeneuve   +18 more
wiley   +1 more source

Immune Checkpoint Inhibitor‐Associated Myocarditis With Myositis/Myasthenia Gravis Overlap Syndrome: Two Case Reports Highlighting Early Onset, Diagnostic Uncertainty, and Management Considerations

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Custom illustration created by the author in collaboration with the Mayo Clinic Digital Media Department. ABSTRACT Immune checkpoint‐inhibitors (ICIs) have revolutionized and significantly improved cancer care through remarkable efficacy, but significant adverse effects have been observed.
Artur Schneider   +3 more
wiley   +1 more source

Two steps forward, one step back: Mycophenolate mofetil treatment for myasthenia gravis in the united states

open access: green, 2015
Ted M. Burns   +5 more
openalex   +2 more sources

Multidimensional Assessment of Neurological Adverse Reactions Related to PD‐1 Inhibitors: A Real‐World Pharmacovigilance Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This pharmacovigilance study systematically analyzed PD‐1 inhibitor–associated neurological adverse events using FAERS data from 2014 to 2024. Central nervous system toxicities, including encephalitis and brainstem encephalitis, were most prominent. Older age, female sex, specific cancer types, and combination therapies increased the risk, with most ...
Xiaofeng Hu   +12 more
wiley   +1 more source

Development and External Validation of a Multivariable Model to Predict Early Minimal Symptom Expression Response in Adult Generalized Myasthenia Gravis Patients Treated With Efgartigimod

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
A multicenter adult gMG cohort from five tertiary centers in China (N = 118) received efgartigimod 10 mg/kg IV weekly × 4. Early minimal symptom expression (MSE) response was defined as MG‐ADL ≤ 1 sustained ≥ 4 weeks and assessed within 4 weeks. A three‐factor nomogram (bulbar MG‐ADL subscore, FVC% predicted, serum IgG) was developed in the derivation ...
Yufang Yang   +12 more
wiley   +1 more source

Pharmacovigilance Insights Into Immune Checkpoint Inhibitor‐Induced Risk of Paraneoplastic Syndrome: A Large‐Scale Real World Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Immune checkpoint inhibitors are associated with rare but severe paraneoplastic syndromes, particularly in lung cancer patients. PS onset shows a bimodal pattern, with increased severity seen in combination therapies like durvalumab plus tremelimumab.
Bufu Tang   +12 more
wiley   +1 more source

Myasthenia Gravis [PDF]

open access: yesPostgraduate Medical Journal, 1965
openaire   +2 more sources

Foundational Principles for the Quantitative Translation of T‐Cell Therapeutics for Hematologic Malignancies and Immunology

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 33-45, January 2026.
T‐cell engaging antibodies (TCEs) and chimeric antigen receptor (CAR) T cells (CAR‐T cells) are among precision medicine therapies that have revolutionized the treatment of hematologic cancers. Their success in oncology has piqued interest in translating this promise into additional indications, such as autoimmune disorders.
Peter Ashcroft   +6 more
wiley   +1 more source

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