Results 111 to 120 of about 52,744 (222)
ABSTRACT Thymoma‐associated myasthenia gravis (TAMG) is frequently refractory, particularly when complicated by myasthenic crisis in advanced invasive disease. Complement C5 inhibitors and neonatal Fc receptor (FcRn) inhibitors have expanded the treatment of acetylcholine receptor (AChR) antibody‐positive generalized myasthenia gravis; however, their ...
Yuta Kizuka +9 more
wiley +1 more source
We identify four distinct C5 inhibitory epitopes, including two novel antibodies that selectively block membrane attack complex (MAC) assembly while preserving C5 cleavage and C5a generation. These findings establish selective MAC inhibition as a new therapeutic strategy for complement‐mediated diseases.
Rebekah Sian Cooke +5 more
wiley +1 more source
Chaoying Liu,1– 3 Simei Ning,1 Ping Lu,1,2 Wenli Jia,1 Xiaohe Zhang,1– 3 Guoyan Qi1– 31Treatment Center of Myasthenia Gravis, Shijiazhuang People’s Hospital, Shijiazhuang, Hebei, People’s Republic of China; 2Hebei Provincial Key Laboratory of Myasthenia ...
Liu C +5 more
doaj
Successful use of sugammadex for caesarean section in a patient with myasthenia gravis
Myasthenia gravis is an autoimmune disorder that is characterized by muscle weakness that fluctuates, worsening with exertion, and improving with rest. Diagnosis of myasthenia gravis is made following clinical and physical examination and is confirmed by
Lokman Soyoral +3 more
doaj +1 more source
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn +17 more
wiley +1 more source
Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley +1 more source
Chaoying Liu,1– 3 Wenli Jia,1 Ping Lu,1 Simei Ning,1 Guoyan Qi1– 31Treatment Center of Myasthenia Gravis, Shijiazhuang People’s Hospital, Shijiazhuang, Hebei, People’s Republic of China; 2Hebei Provincial Key ...
Liu C, Jia W, Lu P, Ning S, Qi G
doaj
Poster, "Neoplasia Associated Ocular Myasthenia Gravis: Primary Renal Tumor in Two Patients with Newly Diagnosed Ocular Myasthenia ...
Susan Andracchi
core

