Results 121 to 130 of about 52,744 (222)

Clusterin is enriched in plaque‐associated astrocytes and localizes to synapses in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION The clusterin gene (CLU) is a top genome‐wide association studies (GWAS) risk locus for Alzheimer's disease (AD) and elevated clusterin levels have been reported in AD biofluids and brain tissue. Despite growing interest in clusterin as a biomarker and therapeutic target, its cellular and subcellular localization in the human ...
Robert A. J. Byrne, Aurora Veteleanu, Hannah L. Cramp, Olivia G. Bacon, Kirsten L. Baillie, Matthew Bright, Rebekah S. Cooke, Gareth D. Fenn, Mariana Flores Castelán, Kok Yung Lee, Wioleta M. Zelek, B. Paul Morgan, Nikoleta Daskoulidou   +12 more
wiley   +1 more source

Acquired myasthenia gravis in childhood.

, 2010
PURPOSE OF REVIEW: This review discusses recent studies on myasthenia gravis with onset in childhood (juvenile myasthenia gravis) and neonatal myasthenia gravis.
Evoli, Amelia, Amelia Evoli
core   +1 more source

Current advances in 2025: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee

Transfusion, EarlyView.
Nabiha H. Saifee, Jennifer Andrews, Mary Berg, Stella T. Chou, Mischa Covington, Elizabeth P. Crowe, Ruchika Goel, Juliana A. Guarente, Tina Ipe, Jeremy W. Jacobs, Jessica Jacobson, Cyril Jacquot, Jenna Khan, Thane A. Kubik, Theodros Mamo, Michael F. Murphy, Kerry O'Brien, Monica B. Pagano, Anil K. Panigrahi, Jacqueline N. Poston, Scott E. Potter, Simon J. Stanworth, Moritz Stolla, Alyssa Ziman, Ryan A. Metcalf   +24 more
wiley   +1 more source

Real‐World Clinical Outcomes and Corticosteroid Tapering in Telitacicept‐Based Therapy for Ocular Myasthenia Gravis: An Exploratory Analysis by Prior Treatment History

Brain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Introduction Ocular myasthenia gravis (OMG) is an autoantibody‐mediated disease characterized by extraocular muscle weakness. Telitacicept has shown potential in treating autoimmune diseases, but its efficacy and corticosteroid‐tapering outcomes in OMG remain unexamined.
Siyu Xie, Wenli Song, Ran Guo, Chunrong Li, Manman Zhang, Yifan Cheng, Wenting Guo, Bo Jin, Jia Li, Yiqi Wang   +9 more
wiley   +1 more source

Mycophenolate mofetil for myasthenia gravis: a clear and present controversy

, 2008
Chad Heatwole, Emma CiafaloniDepartment of Neurology, The University of Rochester, Rochester, New York, USAAbstract: Mycophenolate mofetil (MMF) has been used to treat myasthenia gravis (MG) for over 10 years.
Emma Ciafaloni, Chad Heatwole
core  

Myasthenia gravis

, 2007
ZusammenfassungDie erworbene Myasthenia gravis ist eine seltene autoimmunologische Erkrankung der neuromuskulären Signaltransduktion, die durch Autoantikörper gegen den nikotinischen Azetylcholinrezeptor an der muskulären Endplatte und in seltenen Fällen
F. Zipp, J. Dörr
core   +1 more source

α‐Glucosidase and Acetylcholinesterase (AChE) Inhibitory Activities, Larvicidal Potential and GC–MS Analysis of Endlicheria paniculata: A Combined Experimental and Molecular Docking Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study investigates the essential oil composition of E. paniculata wood, bark, and leaves by GC–MS. Biological evaluations of the leaf essential oil reveal promising larvicidal potential against Aedes aegypti and in vitro inhibitory activities against α‐glucosidase and acetylcholinesterase (AChE), supported by molecular docking simulations ...
Jenifer Priscila de Araujo, Luiz Everson Da Silva, Wanderlei do Amaral, Michele Debiasi Alberton, Ana Helena Loos Moritz, Fernando Cesar Martins Betim, Deise Prehs Montrucchio, Marilis Dallarmi Miguel, Josiane de Fátima Gaspari Dias, Hélcio Silva Dos Santos, Emmanuel Silva Marinho, Márcia Machado Marinho, Jacilene Silva, Obdulio Gomes Miguel   +13 more
wiley   +1 more source

Imine Reductase‐Mediated Regio‐ and Stereoselective Reductive Amination of Diamines

ChemCatChem, Volume 18, Issue 19, 14 October 2026.
Imine reductases (IREDs) have been employed as biocatalysts for the regioselective modification of diamines via reductive amination. The use of racemic diamines resulted in both regio‐ and enantio‐selective reductive amination via kinetic resolution. The application of this methodology has been demonstrated on a preparative scale by the synthesis of a ...
Arnau Rué Casamajo, Yuqi Yu, Lucian Pirvu, Christian Schnepel, Simon J. Charnock, Francesco Falcioni, Martin A. Hayes, Nicholas J. Turner   +7 more
wiley   +1 more source

Myasthenia gravis: A study from India

, 2010
Background: We present the findings from the largest hospital-based studies on myasthenia gravis from India, using data collected over a period of 43 years from the Neurology Department in a tertiary referral center in India.
Menon, Suresh, Bhatia, Nisha S., Umesh, T., Singhal, B.S.   +3 more
core   +1 more source

Familial Autoimmune Myasthenia Gravis (Report Of 3 Cases)

Annals of Indian Academy of Neurology, 2003
Familial Autoimmune myasthenia gravis is rare, occurring in only about 1.3% cases of myasthenia gravis (MG). Here in we report a family with three family members affected by MG. Proband presented with generalised myasthenia where as the other two
Girija A. S, Madhukar M, John John K
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