Results 141 to 150 of about 91,972 (285)

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

open access: yesBJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui   +2 more
wiley   +1 more source

Study on the clinical and electrophysiological characteristics of nerve function in myasthenia gravis patients in Vietnam

open access: yesSAGE Open Medicine
Background: In Vietnam, there is limited research on the role of nerve conduction in myasthenia gravis and its association with clinical features. Objective: This study aims to describe the electrophysiological features in patients with myasthenia gravis.
Tho Kieu Anh Pham   +7 more
doaj   +1 more source

Lineage tree analysis of immunoglobulin variable-region gene mutations in autoimmune diseases: chronic activation, normal selection [PDF]

open access: yes, 2006
Autoimmune diseases show high diversity in the affected organs, clinical manifestations and disease dynamics. Yet they all share common features, such as the ectopic germinal centers found in many affected tissues.
Abraham, R.S.   +9 more
core   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Two Botulinum Toxin A Injections in Patients With Chronic Orofacial Myalgia: A Randomised, Double‐Blind, Controlled Multicenter Trial With Nine‐Month Follow‐Up

open access: yesJournal of Oral Rehabilitation, EarlyView.
Seventy‐two patients were enrolled and sixty‐nine completed the study. Between baseline and all follow‐up visits there was a significant decrease in VAS pain intensity for both groups, but the difference between groups was not significant. ABSTRACT Background Conventional treatment for reducing pain is not always successful in patients with chronic ...
Christine Lennartsson   +4 more
wiley   +1 more source

Myasthenia gravis patients with anti-MuSK antibodies [Miastenija gravis kod bolesnika s pozitivnim protutijelima na MuSK] [PDF]

open access: yes, 2009
In myasthenia gravis (MG) patients without detectable anti-acetylcholine receptor (anti-AChR) antibody, referred to as seronegative myasthenia gravis patients, there is a variable proportion of patients with antibodies against the muscle specific kinase (
Bilić, Ervina   +5 more
core  

Eculizumab improves fatigue in refractory generalized myasthenia gravis [PDF]

open access: yes, 2019
Purpose: To evaluate the effect of eculizumab on perceived fatigue in patients with anti-acetylcholine receptor antibody-positive, refractory, generalized myasthenia gravis (MG) using the Quality of Life in Neurological Disorders (Neuro-QOL) Fatigue ...
Andersen, Henning   +7 more
core   +2 more sources

Technical considerations and review of urinary microRNAs as biomarkers for chronic kidney disease in dogs and cats

open access: yesVeterinary Clinical Pathology, EarlyView.
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley   +1 more source

Swallowing impairment in neurologic disorders : the role of videofluorographic swallowing study [PDF]

open access: yes, 2018
Patients with neurologic diseases almost inevitably develop various degrees of swallowing disorders during their life. Dysphagia is one of the main negative prognostic factors in this class of patients, leading to severe morbidity (i.e.

core   +1 more source

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