Results 201 to 210 of about 91,972 (285)

Sulphonylureas as Adjunct Therapeutic Agents in the Treatment of Autoimmune Conditions: A Narrative Review

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
NLRP3 Inflammasome activation drives inflammatory responses through the production and activation of pro‐inflammatory cytokines. Repurposing sulphonylureas and their derivatives to target NLRP3 may act as adjunct therapeutics for autoimmune conditions. ABSTRACT A rapid and cost‐effective arm of the drug discovery and development process is finding new ...
Jasen Elford   +4 more
wiley   +1 more source

Developing an international concept‐based curriculum for pharmacology education: The promise of core concepts and concept inventories

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2142-2150, August 2025.
Abstract Over recent years, studies have shown that science and health profession graduates demonstrate gaps in their fundamental pharmacology knowledge and ability to apply pharmacology concepts in practice. This article reviews the current challenges faced by pharmacology educators, including the exponential growth in discipline knowledge and ...
Clare Guilding   +12 more
wiley   +1 more source

Pathogenic Role of Age‐Associated B Cells in Autoimmune Disorders and Myasthenia Gravis

open access: yesClinical and Experimental Neuroimmunology, Volume 16, Issue 3, Page 194-197, August 2025.
ABSTRACT Age‐associated B cell (ABC) is a distinctive B cell subset characterized by CD11c and T‐bet expression that accumulates with aging and in autoimmune conditions. This review summarizes current understanding of ABCs in the immunological function and autoimmune pathogenesis of autoimmune diseases, including myasthenia gravis (MG). ABCs arise when
Hiroyuki Akamine, Akiyuki Uzawa
wiley   +1 more source

Anàlisi del títol d'anticossos anti-achr i la seva correlació clínica en pacients amb miastenia gravis seropositiva [PDF]

open access: yes, 2013
Els anticossos contra el receptor de l'acetilcolina representen el principal mecanisme patogènic en la Miastènia Gravis, però la seva utilitat com a biomarcador durant el seguiment de la malaltia és ...
Illa Sendra, I.   +3 more
core   +1 more source

Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review

open access: yesClinical Oral Implants Research, Volume 36, Issue 8, Page 913-929, August 2025.
ABSTRACT Objectives The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes. Material and Methods An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29‐04‐2024.
Emil Hyldahl   +2 more
wiley   +1 more source

Neuromuscular transmission in myasthenia gravis

open access: green, 1953
H. C. Churchill‐Davidson   +1 more
openalex   +1 more source

بررسی وضعيت سرولوژيک و الکتروفيزيولوژيک بيماران مبتلا به مياستنی گراويس [PDF]

open access: yes, 2013
زمينه و هدف: مياستنی گراويس نوعی اختلال خود ايمنی است که به طور اساسي در اثر آنتی بادی‌های ضد رسپتور استيل کولين در محل اتصال عصب به عضله ايجاد شده و کاهش رسپتورهای مذکور سبب اختلال در انتقال نوروترانسميتر و خستگی و ضعف عضلانی می‌شود.
اميرزرگر, علی اکبر   +6 more
core  

Safety and Efficacy of a Neonatal Fc Receptor Antagonist in Patients With Anti‐NMDAR Encephalitis

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
Efgartigimod reduces IgG recycling and promotes the degradation of IgG and pathogenic autoantibodies. Efgartigimod treatment for anti‐NMDA receptor encephalitis was associated with no apparent adverse effects and accelerated improvements in neurological dysfunction and clinical symptoms, particularly cognitive function.
Zhihong Bian   +8 more
wiley   +1 more source

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