Results 71 to 80 of about 91,972 (285)

Identification of potential prognostic biomarkers of thymoma with myasthenia gravis based on serum proteomics

Frontiers in Immunology
BackgroundThymoma is often associated with myasthenia gravis (MG), and the resection of thymoma improves myasthenic symptoms in patients with thymoma and MG (TMG), but some patients still have no relief.
Xiaoting Lin, Xiaoting Lin, Xiaoting Lin, Xiaoting Lin, Peng Liu, Peng Liu, Peng Liu, Peng Liu, Guoyan Qi, Guoyan Qi, Guoyan Qi, Guoyan Qi   +11 more
doaj   +1 more source

Thymoma with Myasthenia Gravis in Adolescent [PDF]

, 2011
Thymomas are exceedingly rare in the first 20 years of life, Thymic lesions comprise approximately 2–3% of all pediatric mediastinal tumors and include thymic cysts, hyperplasia, carcinoma, and thymomas.
Balaiah, K, Nayak, Ganesh, Shetty, Prasad K, Shetty, Prasanna K   +3 more
core   +1 more source

High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li, Binbin Xue, Jia Li, Dewei Xie, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Xu Zhang, Junhui Xia, Jie Lin   +10 more
wiley   +1 more source

Antagonism of the Neonatal Fc Receptor as an Emerging Treatment for Myasthenia Gravis

Frontiers in Immunology, 2020
Myasthenia gravis is an autoimmune disease in which immunoglobulin G (IgG) autoantibodies are formed against the nicotinic acetylcholine receptor (AChR) or other components of the neuromuscular junction.
K. Gable, J. Guptill
semanticscholar   +1 more source

A nurse-led nomogram for predicting the risk of myasthenic crisis in patients with myasthenia gravis and bulbar weakness

BMC Neurology
Background The present study aimed to develop and validate a nurse-led clinical prediction model for assessing the risk of myasthenic crisis (MC) in myasthenia gravis (MG) patients with bulbar weakness.
Huimin Dong, Mengna Li, Mei Ma, Guoyan Qi   +3 more
doaj   +1 more source

Amifampridine phosphate in the treatment of muscle-specific kinase myasthenia gravis: a phase IIb, randomized, double-blind, placebo-controlled, double crossover study

SAGE Open Medicine, 2018
Objective: The aim of this study is to determine the safety and the efficacy of amifampridine phosphate in muscle-specific kinase antibody-positive myasthenia gravis, in a 1:1 randomized, double-blind, placebo-controlled, switchback, double crossover ...
Silvia Bonanno, Maria Barbara Pasanisi, Rita Frangiamore, Lorenzo Maggi, Carlo Antozzi, Francesca Andreetta, Angela Campanella, Greta Brenna, Lorenzo Cottini, Renato Mantegazza   +9 more
doaj   +1 more source

Features of depression development in myasthenia gravis.

Medičnì Perspektivi, 2020
The relative risk of developing depression in myasthenia gravis is 2.14 times higher than in the general population. The features of depression in myasthenia patients remain poorly understood and need to be clarified.
O. I. Kalbus, S. O. Makarov, N. P. Shastun, O. V. Somilo, Yu. V. Bukreyeva   +4 more
doaj   +1 more source

Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. [PDF]

PLoS ONE, 2014
The mechanisms that underlie the development and maintenance of autoimmunity in myasthenia gravis are poorly understood. In this investigation, we evaluate the role of survivin, a member of the inhibitor of apoptosis protein family, in humans and in two ...
Linda L Kusner, Michael J Ciesielski, Alexander Marx, Henry J Kaminski, Robert A Fenstermaker   +4 more
doaj   +1 more source

Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who experienced worsening spastic paraparesis and neurogenic bladder dysfunction.
Jiahui Zeng, Wotu Tian, Jingran Yang, Yanping Yang, Li Cao, Xinghua Luan   +5 more
wiley   +1 more source

Anti-MuSK-positive myasthenia gravis diagnosed during pregnancy: New challenges for an old disease [PDF]

, 2015
Myasthenia gravis is an autoimmune disorder affecting predominantly women in their reproductive age. The course of the disease during pregnancy is unpredictable, although it is more difficult to manage earlier in the gestation.
Matos, A, Monteiro, P, Neves, AR, Santos-Silva, I   +3 more
core   +1 more source