Results 71 to 80 of about 80,519 (274)

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

Autoantibodies in myasthenia gravis: demonstration of anti-motor endplate antibody and anti-muscle membrane antibody using membrane immunofluorescence technique [PDF]

, 1975
The presence of specific serum antibodies in five myasthenia gravis patients was demonstrated against the motor endplates and muscle membranes of rats by membrane immunofluorescence technique.
Arimori, Shigeru, Ichikawa, Yukinobu, Kobashi, Hidehiro, Koriyama, Kenji, Nakata, Yasunari, Tada, Shinya   +5 more
core   +1 more source

Identification of Antibodies to Chondrocyte and Synoviocyte Antigens in Equine Osteoarthritis

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Innate immune responses within the joint are now known to play a key role in osteoarthritis (OA) pathogenesis. However, comparatively little is known regarding the role of adaptive immune responses in OA, and whether they may be important for initiating and sustaining progressive low‐level joint inflammation.
Peter Linde, Jade Kurihara, Lyndah Chow, Zoë J. Williams, Dean Hendrickson, Luke Bass, Steven Dow, Lynn M. Pezzanite   +7 more
wiley   +1 more source

Serum fibrinogen is not elevated in patients with myasthenia gravis

Scientific Reports
Myasthenia gravis (MG) is an autoimmune, autoantibody-mediated disease characterized by fatigable weakness of skeletal muscles. MG is a heterogeneous disease that currently lacks a robust biomarker for diagnosing all subtypes.
Taylor A. Bauman, Sean M. Lee, Vern C. Juel, Yingkai Li, Karli Gilbert, Jiaxin Chen, Henry J. Kaminski, Linda L. Kusner, MGNet Investigators   +8 more
doaj   +1 more source

Імунологічні підтипи міастенії серед дорослих хворих в Україні [PDF]

, 2018
Метою даної роботи стало вивчення імунологічного підтипу у хворих на міастенію. Об’єктом дослідження був імунологічний підтип у хворих на міастенію шляхом виявлення антитіл до рецепторів ацетилхоліну та/або антитіл до м’язово-специфічної тирозин-кінази у
Кальбус, О.І.
core  

Ruolo delle heat shock proteins nella patogenesi della miastenia gravis [PDF]

, 2010
Myasthenia Gravis (MG) is an autoimmune disorder of the neuromuscolar junction mediated by specific antibodies to the nicotinic acetylcholine receptors. Several clinical and experimental studies have confirmed that the HSPs are involved in the process of
MARINO GAMMAZZA, Antonella, ZUMMO, Leila
core   +1 more source

Anti-MuSK-positive myasthenia gravis diagnosed during pregnancy: New challenges for an old disease [PDF]

, 2015
Myasthenia gravis is an autoimmune disorder affecting predominantly women in their reproductive age. The course of the disease during pregnancy is unpredictable, although it is more difficult to manage earlier in the gestation.
Matos, A, Monteiro, P, Neves, AR, Santos-Silva, I   +3 more
core   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

Disfagia e Disartria. Forma Invulgar de Apresentação da Miastenia Gravis [PDF]

, 2007
Myasthenia Gravis is an autoimmune disorder that generally presents with ocular symptoms, specially diplopia and ptosis. Dysphagia may be a manifestation of the generalised type of the disease, but rarely is its presenting feature. The authors describe a
Alcântara, J, Claro, I, Ferreira, S, Lage, P, Nobre Leitão, C, Nunes, J   +5 more
core  

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source