Results 71 to 80 of about 46,950 (237)

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo   +10 more
wiley   +1 more source

A diagnostic score for anti‐myelin‐associated‐glycoprotein neuropathy or chronic inflammatory demyelinating polyradiculoneuropathy in patients with anti‐myelin‐associated‐glycoprotein antibody

open access: yesEuropean Journal of Neurology, Volume 30, Issue 2, Page 501-510, February 2023., 2023
In this study, Doneddu et al. developed a score that permitted an accurate discrimination, amongst patients with anti‐myelin‐associated‐glycoprotein (anti‐MAG) antibodies, of patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and patients with anti‐MAG neuropathy.
Pietro E. Doneddu   +12 more
wiley   +1 more source

On the response of gravitational antennas to dilatonic waves [PDF]

open access: yesPhys.Lett. B470 (1999) 67-72, 1999
It is pointed out that the coupling of macroscopic test masses to the gravi-dilaton background of string theory is non geodesic, in general, and cannot be parametrized by a Brans-Dicke model of scalar-tensor gravity. The response of gravitational antennas to dilatonic waves should be analyzed through a generalized equation of geodesic deviation, taking
arxiv   +1 more source

GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration

open access: yesAlzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION We examined how abnormal prefrontal neurophysiology and changes in gamma‐aminobutyric acid‐ergic (GABAergic) neurotransmission contribute to behavioral impairments in disorders associated with frontotemporal lobar degeneration (FTLD). METHODS We recorded magnetoencephalography during an adaptive visuomotor task from 11 people with
Laura E. Hughes   +11 more
wiley   +1 more source

Role of autoantibody levels as biomarkers in the management of patients with myasthenia gravis: A systematic review and expert appraisal

open access: yesEuropean Journal of Neurology, Volume 30, Issue 1, Page 266-282, January 2023., 2023
Myasthenia gravis is recognized as an immunoglobulin G autoantibody‐mediated disease, but the relationship between autoantibody levels and disease activity is unclear. We conducted a systematic literature review to evaluate this landscape, which yielded 10 studies mainly describing a positive, significant correlation.
Andreas Meisel   +13 more
wiley   +1 more source

Serum fibrinogen is not elevated in patients with myasthenia gravis

open access: yesScientific Reports
Myasthenia gravis (MG) is an autoimmune, autoantibody-mediated disease characterized by fatigable weakness of skeletal muscles. MG is a heterogeneous disease that currently lacks a robust biomarker for diagnosing all subtypes.
Taylor A. Bauman   +8 more
doaj   +1 more source

Myasthenia gravis as one of paraneoplastic neurological syndromes associated with small cell lung cancer. Case report

open access: yesNeurologijos seminarai, 2018
Myasthenia gravis associated with extrathymic malignancies is a rarely diagnosed pathology in clinical practice. We report a case of myasthenia gravis-like syndrome associated with small cell lung cancer.
R. Bunevičiūtė   +2 more
doaj   +1 more source

Generalization of Schwinger-Zwanziger Dyon to Quaternion [PDF]

open access: yes, 2010
Postulating the existence of magnetic monopole in electromagnetism and Heavisidian monopoles in gravitational interactions, a unified theory of gravi-electromagnetism has been developed on generalizing the Schwinger-Zwanziger formulation of dyon to quaternion in simple and consistent manner.
arxiv   +1 more source

Association of myasthenia gravis and Behçet's disease: A case report [PDF]

open access: yes, 1970
Myasthenia gravis is a disease of neuromuscular junction due to auto-immune destruction of the acetylcholine receptors. Behçet's disease, on the other hand, is a multisystemic vascular-inflammatory disease.
Batum, Melike   +5 more
core   +2 more sources

Clinical picture and treatment of myasthenia gravis in the adult population [PDF]

open access: yes, 2022
Introduction and purpose: Myasthenia gravis (MG, myasthenia gravis ) is a classic example of an autoimmune disease caused by antibodies against acetylcholine receptors ( AChR) , muscle-specific kinase (MuSK) or other AChR-related proteins in the ...
Blicharz, Agnieszka   +4 more
core   +2 more sources

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