Results 81 to 90 of about 61,118 (253)

Consistent improvement with eculizumab across muscle groups in myasthenia gravis

Annals of Clinical and Translational Neurology, 2020
Objective To assess whether eculizumab, a terminal complement inhibitor, improves patient‐ and physician‐reported outcomes (evaluated using the myasthenia gravis activities of daily living profile and the quantitative myasthenia gravis scale ...
Renato Mantegazza, Fanny L. O'Brien, Marcus Yountz, James F. Howard Jr, for the REGAIN study group   +4 more
doaj   +1 more source

Disfagia e Disartria. Forma Invulgar de Apresentação da Miastenia Gravis [PDF]

, 2007
Myasthenia Gravis is an autoimmune disorder that generally presents with ocular symptoms, specially diplopia and ptosis. Dysphagia may be a manifestation of the generalised type of the disease, but rarely is its presenting feature. The authors describe a
Alcântara, J, Claro, I, Ferreira, S, Lage, P, Nobre Leitão, C, Nunes, J   +5 more
core  

MendelR: A One‐Stop R Toolkit for Mendelian Randomization Analysis

Med Research, EarlyView.
ABSTRACT MendelR is a fully automated R package specifically developed for Mendelian randomization (MR) studies, designed to address the technical challenges of causal inference in biomedical research. As a powerful causal inference method, Mendelian randomization can effectively reduce confounding bias in observational studies.
Xiaohong Ke, Kailai Li, Anqi Lin, Yasi Zhang, Peng Luo   +4 more
wiley   +1 more source

Experience Using Efgartigimod to Treat Juvenile Myasthenia Gravis in China: A Multicenter Retrospective Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Current therapeutic management of juvenile myasthenia gravis (JMG) predominantly relies on conventional immunosuppressive therapies and expert consensus extrapolated from adult data, creating a critical gap in high‐quality, pediatric‐specific clinical evidence.
Jing Lin, Guoyan Qi, Susan Luo, Qilong Jiang, Bitao Bu, Min Liu, Yuzhen Wei, Meigui Han, Junhong Yang, Zhilan Zhao, Lili Zhang, Yifan Zhang, Haoyou Xu, Xingjie Hao, Zhijun Li   +14 more
wiley   +1 more source

Identification of metabolic biomarkers and therapeutic targets in the thymoma-associated myasthenia gravis treated with methylprednisolone

Discover Oncology
Objective This study aims to screen and identify metabolic biomarkers and targets for methylprednisolone treatment of thymoma with myasthenia gravis (MG) through metabolomics and network pharmacology analysis, thereby improving guidance for clinical ...
Shanshan Gu, Xu Wang, Hongxia Yang, Yaxuan Wang, Congya Yan, Xiaoting Lin, Peng Liu, Lu Liu, Li Meng, Guoyan Qi   +9 more
doaj   +1 more source

Determinants of quality of life in Brazilian patients with myasthenia gravis

Clinics
OBJECTIVES: The aims of the current study were 1) to evaluate the reliability and validity of the Brazilian version of the 15-item Myasthenia Gravis Quality of Life Scale and 2) to investigate the quality of life of Brazilian patients with myasthenia ...
Aline Mansueto Mourão, Rodrigo Santiago Gomez, Luiz Sergio Mageste Barbosa, Denise da Silva Freitas, Elizabeth Regina Comini-Frota, Arthur Kummer, Stella Maris Aguiar Lemos, Antonio Lucio Teixeira   +7 more
doaj   +1 more source

Takotsubo syndrome in patients with myasthenia gravis: a systematic review of previously reported cases

BMC Neurology, 2019
Background Myasthenia gravis associated takotsubo syndrome is a rare condition. This study aimed to explore its typical presentation, investigations and treatment through a systematic review of previously reported cases.
Devarajan Rathish, Minuri Karalliyadda
doaj   +1 more source

a pilot study [PDF]

, 2015
Muscular weakness in myasthenia gravis (MG) is commonly assessed using Quantitative Myasthenia Gravis Score (QMG). More objective and quantitative measures may complement the use of clinical scales and might detect subclinical affection of muscles.
Brandt, Alexander U., Hoffmann, Sarah, Kohler, Siegfried, Meisel, Andreas, Paul, Friedemann, Piper, Sophie K., Reilmann, Ralf, Sass, Christian, Siedler, Jana   +8 more
core   +1 more source

Increased Prevalence of Extrathymic Neoplasms in Myasthenia Gravis Patients‐A Population‐Based, Matched Case–Control Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Myasthenia gravis (MG) is associated with thymic neoplasms. However, an increased prevalence of extrathymic neoplasms has also been reported. This study aimed to evaluate the rates of malignancy in MG patients while accounting for risk factors such as disease characteristics and immunomodulatory treatments.
Keshet Pardo, Tasneem Kab, Mark A. Hellmann, Itay Lotan, Tzippy Shochat, Nadav Loebl, Bar Yacobi, Yitzhak Friedman, Leor Perl, Nitai Shimon, Yiska Loewenberg Weisband, Liya Bieber, Eitan Auriel, Adi Wilf‐Yarkoni   +13 more
wiley   +1 more source

The prognosis of MG patients with different thymic pathology: a multicenter retrospective cohort study

BMC Medicine
Background To identify the associations between thymic pathology and the prognosis of myasthenia gravis (MG) patients. Methods In this multicenter retrospective study, 1,254 myasthenia gravis (MG) patients who underwent thymectomy across four clinical ...
Moli Fan, Hao Zhang, Yutong Shi, Xiaoyu Huang, Ying Cui, Zihao Yu, Xiao-He Zhang, Xiao-Jing Zhang, Ying-Ping Xue, Lei Huang, Fu-Dong Shi, Guo-Yan Qi   +11 more
doaj   +1 more source