Results 71 to 80 of about 61,118 (253)

Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring

Annals of Clinical and Translational Neurology, EarlyView.
Francesco Saccà, Ryan Pelto
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

A case of myasthenia gravis following alopecia areata

Journal of Cutaneous Immunology and Allergy, 2023
We present a case of myasthenia gravis that occurred after alopecia areata and evaluate the literature on the comorbidity of alopecia and myasthenia gravis. A 41‐year‐old male noticed hair loss on his scalp 4 months ago, and his hair loss progressed with
Naoki Sasaki, Yu Sawada
doaj   +1 more source

Імунологічні підтипи міастенії серед дорослих хворих в Україні [PDF]

, 2018
Метою даної роботи стало вивчення імунологічного підтипу у хворих на міастенію. Об’єктом дослідження був імунологічний підтип у хворих на міастенію шляхом виявлення антитіл до рецепторів ацетилхоліну та/або антитіл до м’язово-специфічної тирозин-кінази у
Кальбус, О.І.
core  

Brazilian cross-cultural translation and adaptation of the Questionnaire of Life Quality Specific for Myasthenia Gravis-15 items [PDF]

, 2013
Objective: To translate and to perform the cross-cultural adaptation of the Questionnaire of Life Quality Specific for Myasthenia Gravis - 15 items (MG-QOL15). Method: the original English version of the questionnaire was translated into Portuguese. This
Araujo, Caroline Martins, Barbosa, Luiz Sergio Mageste, Burns, Ted M., Gomez, Rodrigo Santiago, Lemos, Stela Maris Aguiar, Mourao, Aline Mansueto, Teixeira, Antonio Lúcio   +6 more
core   +2 more sources

Reply to Letter: “Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring” by Saccà and Pelto Regarding “Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab”

Annals of Clinical and Translational Neurology, EarlyView.
Lea Gerischer, Jutta Schroeder‐Braunstein, Guido Wabnitz, Andreas Meisel   +3 more
wiley   +1 more source

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

iMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu, Tao Wen, Nan Shang, Penghao Xie, Zhenyu Wang, Hang Li, Shaobo Li, Dequan Zhang   +7 more
wiley   +1 more source

Anti-MuSK-positive myasthenia gravis diagnosed during pregnancy: New challenges for an old disease [PDF]

, 2015
Myasthenia gravis is an autoimmune disorder affecting predominantly women in their reproductive age. The course of the disease during pregnancy is unpredictable, although it is more difficult to manage earlier in the gestation.
Matos, A, Monteiro, P, Neves, AR, Santos-Silva, I   +3 more
core   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Exploring the depths of IgG4: insights into autoimmunity and novel treatments

Frontiers in Immunology
IgG4 subclass antibodies represent the rarest subclass of IgG antibodies, comprising only 3-5% of antibodies circulating in the bloodstream. These antibodies possess unique structural features, notably their ability to undergo a process known as fragment-
Selen Ünlü, Selen Ünlü, Blanca G. Sánchez Navarro, Elif Cakan, Daniel Berchtold, Rafael Meleka Hanna, Secil Vural, Secil Vural, Atay Vural, Atay Vural, Andreas Meisel, Miriam L. Fichtner, Miriam L. Fichtner   +12 more
doaj   +1 more source