Results 81 to 90 of about 80,519 (274)

Exploring the depths of IgG4: insights into autoimmunity and novel treatments

Frontiers in Immunology
IgG4 subclass antibodies represent the rarest subclass of IgG antibodies, comprising only 3-5% of antibodies circulating in the bloodstream. These antibodies possess unique structural features, notably their ability to undergo a process known as fragment-
Selen Ünlü, Selen Ünlü, Blanca G. Sánchez Navarro, Elif Cakan, Daniel Berchtold, Rafael Meleka Hanna, Secil Vural, Secil Vural, Atay Vural, Atay Vural, Andreas Meisel, Miriam L. Fichtner, Miriam L. Fichtner   +12 more
doaj   +1 more source

risk factors and impact on quality of life [PDF]

, 2016
Objectives Emerging evidence suggests that fatigue in myasthenia gravis (MG) is a relevant problem that negatively impacts activities of daily living (ADL). The relationship between fatigue and quality of life (QoL) has never been systematically explored
Grittner, Ulrike, Hoffmann, Sarah, Kohler, Siegfried, Meisel, Andreas, Ramm, Johanna, Siedler, Jana   +5 more
core   +1 more source

AI‐Driven Personalized Nutrition: Integrating Omics, Ethics, and Digital Health

Molecular Nutrition &Food Research, EarlyView.
This graphical abstract illustrates the concept of personalized nutrition, incorporating biological, dietary, and lifestyle factors. Artificial intelligence (AI)‐powered data analysis, digital tools and personalized nutrition recommendations target optimizing health and preventing diseases.
Celin Mundt, Büşra Yusufoğlu, Daniel Kudenko, Kerem Mertoğlu, Tuba Esatbeyoglu   +4 more
wiley   +1 more source

Determinants of quality of life in Brazilian patients with myasthenia gravis

Clinics
OBJECTIVES: The aims of the current study were 1) to evaluate the reliability and validity of the Brazilian version of the 15-item Myasthenia Gravis Quality of Life Scale and 2) to investigate the quality of life of Brazilian patients with myasthenia ...
Aline Mansueto Mourão, Rodrigo Santiago Gomez, Luiz Sergio Mageste Barbosa, Denise da Silva Freitas, Elizabeth Regina Comini-Frota, Arthur Kummer, Stella Maris Aguiar Lemos, Antonio Lucio Teixeira   +7 more
doaj   +1 more source

Takotsubo syndrome in patients with myasthenia gravis: a systematic review of previously reported cases

BMC Neurology, 2019
Background Myasthenia gravis associated takotsubo syndrome is a rare condition. This study aimed to explore its typical presentation, investigations and treatment through a systematic review of previously reported cases.
Devarajan Rathish, Minuri Karalliyadda
doaj   +1 more source

A case of myasthenia gravis following alopecia areata

Journal of Cutaneous Immunology and Allergy, 2023
We present a case of myasthenia gravis that occurred after alopecia areata and evaluate the literature on the comorbidity of alopecia and myasthenia gravis. A 41‐year‐old male noticed hair loss on his scalp 4 months ago, and his hair loss progressed with
Naoki Sasaki, Yu Sawada
doaj   +1 more source

Nipocalimab Dose Selection in Generalized Myasthenia Gravis

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Model‐Informed Nipocalimab Dose Selection for Generalized Myasthenia Gravis. ABSTRACT Nipocalimab is a fully human immunoglobulin G (IgG)1 monoclonal antibody (mAb) designed to selectively block the IgG binding site of neonatal fragment crystallizable receptor (FcRn) to inhibit IgG recycling and decrease circulating IgG, including pathogenic IgG ...
Belén Valenzuela, Martine Neyens, Yaowei Zhu, Sindhu Ramchandren, Anne‐Gaëlle Dosne, Jocelyn H. Leu, Ruben Faelens, Leona E. Ling, Juan‐José Pérez‐Ruixo   +8 more
wiley   +1 more source

Identification of metabolic biomarkers and therapeutic targets in the thymoma-associated myasthenia gravis treated with methylprednisolone

Discover Oncology
Objective This study aims to screen and identify metabolic biomarkers and targets for methylprednisolone treatment of thymoma with myasthenia gravis (MG) through metabolomics and network pharmacology analysis, thereby improving guidance for clinical ...
Shanshan Gu, Xu Wang, Hongxia Yang, Yaxuan Wang, Congya Yan, Xiaoting Lin, Peng Liu, Lu Liu, Li Meng, Guoyan Qi   +9 more
doaj   +1 more source

Consistent improvement with eculizumab across muscle groups in myasthenia gravis

Annals of Clinical and Translational Neurology, 2020
Objective To assess whether eculizumab, a terminal complement inhibitor, improves patient‐ and physician‐reported outcomes (evaluated using the myasthenia gravis activities of daily living profile and the quantitative myasthenia gravis scale ...
Renato Mantegazza, Fanny L. O'Brien, Marcus Yountz, James F. Howard Jr, for the REGAIN study group   +4 more
doaj   +1 more source

Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status. [PDF]

, 2007
Am J Pathol. 2007 Sep;171(3):893-905. Epub 2007 Aug 3. Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status.
Adams, Alexander Marx, Angela Vincent, Aurea Canelhas, B. Paul Morgan, Beeson, Berrih, Castleman, Cole, Dashiell, Daveau, Davies, Drachman, Engel, Erik Niks, Evoli, Flores, Fosbrink, Francesco Scaravilli, French, Gasque, Graus, Hageman, Hoch, Hsi, Jan J.G.M. Verschuuren, Kaminski, Kaminski, Kyewski, Lampert, Lauriola, Leite, Lin, MacLennan, MacLennan, Margaret Jones, Maria I. Leite, Mason, Matthews, McConville, Meraouna, Monsinjon, Morgan, Morgan, Morgan, Nakano, Navenot, Nick Willcox, Ohta, Philipp Ströbel, Plested, Pratt, Ralf Gold, Roxanis, Roxanis, Rus, Safar, Sanders, Schluep, Schluep, Shiono, Sims, Sonia Berrih-Aknin, Spreadbury, Sprott, Tzartos, van Beek, Vincent, Vincent, Wakkach, Wekerle, Zhang   +71 more
core   +2 more sources