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Muscle and Nerve, 2023 AbstractMyasthenic crisis (MC) is a life‐threatening manifestation of myasthenia gravis (MG) defined by respiratory insufficiency that requires the use of invasive or non‐invasive ventilation. This is often the result of respiratory muscle weakness but can also be due to bulbar weakness with upper airway collapse.
Yuebing Li, Sung-Min Cho
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Neurocritical Care, 2005
Myasthenic crisis is a serious occurrence, affecting up to 27% of patients with myasthenia gravis. In the approach to the patient with myasthenic crisis, (1) the diagnosis of myasthenia gravis is confirmed; (2) respiratory failure is evaluated and treated in the intensive care unit, while potential precipitating factors are identified and managed; (3 ...
David Lacomis
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Myasthenic crisis is a serious occurrence, affecting up to 27% of patients with myasthenia gravis. In the approach to the patient with myasthenic crisis, (1) the diagnosis of myasthenia gravis is confirmed; (2) respiratory failure is evaluated and treated in the intensive care unit, while potential precipitating factors are identified and managed; (3 ...
David Lacomis
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Current Treatment Options in Neurology, 2004
Myasthenia gravis is the most common disorder of the neuromuscular junction. Myasthenia crisis, defined as respiratory failure requiring mechanical ventilation in myasthenia gravis, is a common life-threatening complication that occurs in approximately 15% to 20% of patients with myasthenia gravis.
Jawad F., Kirmani +2 more
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Myasthenia gravis is the most common disorder of the neuromuscular junction. Myasthenia crisis, defined as respiratory failure requiring mechanical ventilation in myasthenia gravis, is a common life-threatening complication that occurs in approximately 15% to 20% of patients with myasthenia gravis.
Jawad F., Kirmani +2 more
openaire +3 more sources
Predictors of outcome of myasthenic crisis
Neurological Sciences, 2014There is paucity of study on predictors of myasthenic crisis (MC), prolonged ventilation and their outcome, a reason why this study was undertaken. Sixty-four patients with myasthenia gravis (MG) were included whose median age was 45 (6-84) years. Their clinical treatment, presence of thymoma, anti-acetylcholine receptor antibody (AchRAb), thymectomy ...
Jayantee Kalita, Misra U K
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On the Concept of Myasthenic Crisis
Journal of Clinical Neuromuscular Disease, 2002This article reviews controversies surrounding the concept of myasthenic crisis. Literature review and our own experience demonstrate that there is disagreement about how a crisis should be defined, what the implications of a crisis are, whether crises are preventable, and how crisis incidence should be calculated.
Richard S, Bedlack, Donald B, Sanders
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2021
Abstract Acute respiratory failure can be due to a variety of causes, and neuromuscular weakness is an important consideration. Myasthenic crisis identification and management is reviewed.
Sara C. LaHue, Morris Levin
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Abstract Acute respiratory failure can be due to a variety of causes, and neuromuscular weakness is an important consideration. Myasthenic crisis identification and management is reviewed.
Sara C. LaHue, Morris Levin
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Critical Care Medicine, 1997
To investigate the frequency, causes, and characteristic features of the course of isolated myasthenic crisis (defined as acute respiratory failure with the need for mechanical ventilation). To compare the effectiveness of three different therapeutic regimens (i.e., continuous intravenous infusion of pyridostigmine, pyridostigmine plus prednisolone ...
J, Berrouschot +4 more
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To investigate the frequency, causes, and characteristic features of the course of isolated myasthenic crisis (defined as acute respiratory failure with the need for mechanical ventilation). To compare the effectiveness of three different therapeutic regimens (i.e., continuous intravenous infusion of pyridostigmine, pyridostigmine plus prednisolone ...
J, Berrouschot +4 more
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Procainamide-Induced Myasthenic Crisis
Therapeutic Drug Monitoring, 1990We describe a case of procainamide-induced respiratory failure in a myasthenic patient with no prior history of respiratory weakness. Respiratory failure was induced secondary to procainamide alone since no N-acetyl-procainamide level was detectable. The patient's strength rapidly improved and he was successfully extubated 12 h after the offending dose.
P J, Godley +3 more
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Outcomes and treatment of myasthenic crisis
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2016The analysis of fatal outcomes of myasthenic crisis in patients with myasthenia.The data on 19 patients with myastheniccrisis admitted at the Moscow Regional Research and Clinical Institute («MONIKI») over 12 years (1997-2009) have been summarized.There are more than 600 patients with myasthenia in the Moscow region, including 13% patients with onset ...
S V, Kotov, O P, Sidorova
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