Acquisition of clarithromycin resistance mutations in the 23S rRNA gene of Mycobacterium abscessus in the presence of inducible erm(41) [PDF]
, 2017 Objectives Antibiotic therapy of pulmonary Mycobacterium abscessus infection is based on a combination treatment including clarithromycin. Recent data demonstrated that M.
Bloemberg, Guido V. +4 more
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Uveitis with occult choroiditis due to Mycobacterium kansasii: limitations of interferon-gamma release assay (IGRA) tests (case report and mini-review on ocular non-tuberculous mycobacteria and IGRA cross-reactivity) [PDF]
, 2018 Ocular tuberculosis is difficult to diagnose but should be suspected when uveitis fails to respond to inflammation suppressive therapy. Interferon-gamma release assays (IGRAs) represent a substantial help to diagnose suspected ocular tuberculosis ...
Herbort, Carl +2 more
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Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus [PDF]
, 2018 Matthias Richard +5 more
openalex +1 more source
Alternative therapies against Mycobacterium abscessus infections
Clinical Microbiology and InfectionMycobacterium abscessus (Mab) is considered as the most pathogenic rapid-growing mycobacteria in humans, causing pulmonary and extra-pulmonary diseases, especially in patients with cystic fibrosis. Mab shows intrinsic and acquired resistance to many drugs, leaving limited treatment options that lead to a generally poor prognosis.
Palucci, Ivana, Delogu, Giovanni
openaire +2 more sources
WCN26-2390 Tunnel Infections due to Multidrug-Resistant Mycobacterium abscessus Requiring Catheter Removal in a Peritoneal Dialysis Patient [PDF]
Takahiro MORINO +3 more
openalex +1 more source
Erm(41)-dependent inducible resistance to azithromycin and clarithromycin in clinical isolates of Mycobacterium abscessus [PDF]
, 2017 Objectives The ribosomal methylase Erm(41) confers inducible resistance to macrolides in Mycobacterium abscessus. The aim of this work was to systematically study and compare drug susceptibility to clarithromycin and azithromycin in M.
Böttger, Erik C. +4 more
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