To analyze the clinical characteristics of nontuberculous mycobacterial (NTM) ocular infections and the species-specific in vitro antimicrobial susceptibility.In 2000 to 2011 at the National Taiwan University Hospital, multilocus sequencing of rpoB, hsp65 and secA was used to identify NTM isolates from ocular infections.
Hsiao-Sang Chu +2 more
exaly +6 more sources
Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review. [PDF]
This case highlights that ANCA‐associated vasculitis can emerge in patients with chronic airway disease and a history of nontuberculous mycobacterial infection, potentially masquerading as infection‐related inflammation. Early recognition based on extrapulmonary clues (urinary abnormalities and neuropathy) enabled prompt diagnosis and treatment with ...
Takahashi H +11 more
europepmc +2 more sources
Nontuberculous mycobacterium infection in a burn ICU patient
Abstract : Infection is a leading cause of mortality in burn patients, typically due to bacterial pathogens such as staphylococcus aureus and Pseudomonas aeruginosa, less commonly fungi, and possibly viruses. In non burn patients with underlying pulmonary or cutaneous diseases, nontuberculous mycobacteria (NTM) have become an increasingly recognized ...
Boyer, Joseph M. +7 more
openaire +4 more sources
Nontuberculous Mycobacterial Lung Diseases Caused by Mixed Infection with Mycobacterium avium Complex and Mycobacterium abscessus Complex [PDF]
Mycobacterium avium complex (MAC) and M. abscessus complex (MABC) comprise the two most important human pathogen groups causing nontuberculous mycobacterial lung disease (NTM-LD). However, there are limited data regarding NTM-LD caused by mixed NTM infections.
Sun Hye Shin +2 more
exaly +3 more sources
Secondary Pulmonary Alveolar Proteinosis Associated With Ruxolitinib After Bone-Marrow Transplantation: A Case With Transient Improvement Following Drug Discontinuation. [PDF]
Secondary pulmonary alveolar proteinosis (PAP) may occur in patients receiving ruxolitinib for steroid‐refractory GVHD after bone marrow transplantation. In this case, a 47‐year‐old woman developed respiratory failure 8 months after commencing ruxolitinib therapy, and initial radiological and clinical improvements occurred after drug withdrawal, prior ...
Yanagi T +17 more
europepmc +2 more sources
Dual Mycobacterial Infection: Rare Coinfection of Mycobacterium tuberculosis and Nontuberculous Mycobacteria. [PDF]
There is little research on the subject, despite the rising prevalence of concurrent Mycobacterium tuberculosis (MTB) and nontuberculous mycobacteria (NTM) infections. We present the case of a 48-year-old immunocompetent man diagnosed with pulmonary tuberculosis with simultaneous sputum cultures positive for NTM.
Aryal Y +4 more
europepmc +3 more sources
Nontuberculous Mycobacterium Infections Associated With Heater-Cooler Devices [PDF]
Disseminated nontuberculous mycobacterium infections have occurred following surgical procedures involving extracorporeal circulation; contaminated water from heater-cooler devices (HCDs) has been implicated as the source. The purpose of this review was to evaluate the public health concern and to educate physicians who care for this patient population.
Keith B, Allen +9 more
openaire +2 more sources
Pulmonary Infection Caused by an Unusual, Slowly Growing Nontuberculous Mycobacterium [PDF]
ABSTRACT Mycobacterium triplex , a recently described slowly growing nontuberculous mycobacterium, was isolated from a Finnish patient with pulmonary mycobacteriosis. The disease was successfully treated with antimycobacterial drugs.
S, Suomalainen +6 more
openaire +2 more sources
Infection with nontuberculous mycobacterium after injection of adulterated silicone fluid [PDF]
A 57-year-old woman presented with a predominantly right-sided cellulitic area of her buttock after receiving multiple bilateral silicone injections in the buttocks. The workup revealed subcutaneous infection with rapidly growing mycobacteria. Surgical management and etiologic factors are discussed, and a review of the literature is presented.
Kevin R, Knox +3 more
openaire +2 more sources
Treatment of Mycobacterium tuberculosis and Mycobacterium avium infections requires multiple drugs for long time periods. Mycobacterium protein-tyrosine-phosphatase B (MptpB) is a key M. tuberculosis virulence factor that subverts host antimicrobial activity to promote intracellular survival. Inhibition of MptpB reduces the infection burden in vivo and
Rodríguez-Fernández, Pablo +7 more
openaire +6 more sources

