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T-Cell Exhaustion in Mycobacterium tuberculosis and Nontuberculous Mycobacteria Infection: Pathophysiology and Therapeutic Perspectives [PDF]

Microorganisms, 2021
Immune exhaustion is a condition associated with chronic infections and cancers, characterized by the inability of antigen-specific T cells to eliminate the cognate antigen. Exhausted T cells display a peculiar phenotypic profile and exclusive functional
Andrea Lombardi, Simone Villa, Valeria Castelli, Alessandra Bandera, Andrea Gori   +4 more
doaj   +3 more sources

Pulmonary <i>Mycobacterium fortuitum</i> Infection Associated With Achalasia Treated With Peroral Endoscopic Myotomy Alone: A Case Report. [PDF]

Respirol Case Rep
We report a rare case of pulmonary M. fortuitum infection associated with achalasia that improved following treatment of achalasia alone. ABSTRACT Pulmonary infection caused by Mycobacterium fortuitum is uncommon and often occurs in patients with underlying conditions such as achalasia.
Masuda H, Torii R, Yamasaki K, Shingu T, Hata R, Yatera K.   +5 more
europepmc   +2 more sources

Temperature and pH growth preferences predict the pathogenicity and environmental distributions of nontuberculous mycobacteria. [PDF]

mSystems
The genus Mycobacterium is highly diverse, and in addition to Mycobacterium tuberculosis, it includes many other pathogenic and non-pathogenic taxa which are collectively referred to as the nontuberculous mycobacteria. Although a subset of nontuberculous
Gebert MJ, Hasan NA, Pill-Kastens MR, Grant L, Hoffert M, Epperson LE, Strong M, Fierer N.   +7 more
europepmc   +2 more sources

Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions

mBio, 2021
Nontuberculous mycobacteria (NTM) are an important cause of morbidity and mortality in pulmonary infections.
Masayuki Nakajima, Masashi Matsuyama, Mio Kawaguchi, Takumi Kiwamoto, Yosuke Matsuno, Yuko Morishima, Kazufumi Yoshida, Mingma Sherpa, Kai Yazaki, Hajime Osawa, Masafumi Muratani, Yukio Ishii, Nobuyuki Hizawa   +12 more
doaj   +1 more source

A Ventral Hernia-repair–related Mycobacterium mageritense Mesh Infection Treated with NPWT without Mesh Removal

Plastic and Reconstructive Surgery, Global Open, 2021
Summary:. Abdominal hernias are often repaired using prosthetic mesh, which is susceptible to infections. Normally, it is necessary to remove the mesh.
Junji Ando, MD, Riyo Miyata, MD, Masayuki Harada, MD, Mika Takeuchi, MD, Kei Kasahara, MD, PhD, Yuji Yoshimoto, MD, Fumikazu Koyama, MD, PhD, Masamitsu Kuwahara, MD, PhD   +7 more
doaj   +1 more source

Mycobacterium genavense Causing Lung Abscess in an Immunocompetent Individual

Journal of Association of Pulmonologist of Tamil Nadu, 2021
Mycobacterium genavense is a rare nontuberculous mycobacterium, known to cause serious infections in HIV-infected patients and immunocompromised individuals. The diagnosis of M.
Ria Lawrence, R Narasimhan
doaj   +1 more source

Mycobacterium marinum infection of the hand presenting as a nodular skin lesion

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2020
Nontuberculous mycobacteria have emerged as an important group of pathogens worldwide; however, infections of the hand are rare. Infections caused by nontuberculous mycobacteria are often opportunistic in humans, and notoriously difficult to treat due to
Rahul Bollam, Tung Phan
doaj   +1 more source

Mycobacterium abscessus skin infection after tattooing - Case report [PDF]

Anais Brasileiros de Dermatologia, 2015
Mycobacterium abscessus is a rapidly growing mycobacterium that has been affecting people undergoing invasive procedures, such as videosurgery and mesotherapy. This bacterium has global distribution, being found in numerous niches.
Pétra Pereira de Sousa, Rossilene Conceição da Silva Cruz, Antonio Pedro Mendes Schettini, Danielle Cristine Westphal   +3 more
doaj   +2 more sources

Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence

mSystems, 2021
Mycobacteria are naturally resilient, and mycobacterial infections are notoriously difficult to treat with antibiotics, with biofilm formation being the main factor complicating the successful treatment of tuberculosis (TB).
Kirsi Savijoki, Henna Myllymäki, Hanna Luukinen, Lauri Paulamäki, Leena-Maija Vanha-aho, Aleksandra Svorjova, Ilkka Miettinen, Adyary Fallarero, Teemu O. Ihalainen, Jari Yli-Kauhaluoma, Tuula A. Nyman, Mataleena Parikka   +11 more
doaj   +1 more source

Rare enough ? Cardiac Device‐related pocket Infection due to Mycobacterium fortuitum

Clinical Case Reports, 2021
Nontuberculous mycobacteria are rare causes of cardiac implantable electronic device (CIED)‐related infections and may lead to device‐related endocarditis, so preventing them is key. We present a case of CIED‐related pocket infection due to Mycobacterium
Reshma Golamari, Nitasa Sahu, Rama Vunnam, Dhirisha Bhatt, Rameet Thapa, Ravi Patel, Rohit Jain   +6 more
doaj   +1 more source