Treatment of Mycobacterium tuberculosis and Mycobacterium avium infections requires multiple drugs for long time periods. Mycobacterium protein-tyrosine-phosphatase B (MptpB) is a key M. tuberculosis virulence factor that subverts host antimicrobial activity to promote intracellular survival. Inhibition of MptpB reduces the infection burden in vivo and
Rodríguez-Fernández, Pablo +7 more
openaire +6 more sources
Nontuberculous mycobacterium infection in a burn ICU patient
Abstract : Infection is a leading cause of mortality in burn patients, typically due to bacterial pathogens such as staphylococcus aureus and Pseudomonas aeruginosa, less commonly fungi, and possibly viruses. In non burn patients with underlying pulmonary or cutaneous diseases, nontuberculous mycobacteria (NTM) have become an increasingly recognized ...
Boyer, Joseph M. +7 more
openaire +3 more sources
Management of infection with nontuberculosis mycobacteria [PDF]
The nontuberculosis mycobacteria are often naturally resistant to the conventional antibiotics and to antituberculosis drugs (1–3). In addition, providing advice for the treatment of nontuberculosis is complicated by the variable and changing ...
Gillespie, Stephen H. +1 more
core +1 more source
Mycobacterium abscessus is one of the nontuberculous mycobacteria (NTM), which can cause many clinical spectra, predominantly pulmonary infections followed by skin and soft tissue infections.
Abdulrahman F. Al-Mashdali +4 more
doaj +1 more source
Prospecting environmental mycobacteria: combined molecular approaches reveal unprecedented diversity [PDF]
Background: Environmental mycobacteria (EM) include species commonly found in various terrestrial and aquatic environments, encompassing animal and human pathogens in addition to saprophytes.
Tanya T Khera +39 more
core +1 more source
Antimycobacterial Activity of Laurinterol and Aplysin from Laurencia johnstonii
Marine environments represent a great opportunity for the discovery of compounds with a wide spectrum of bioactive properties. Due to their large variety and functions derived from natural selection, marine natural products may allow the identification ...
Sara García-Davis +7 more
doaj +1 more source
La tuberculose humaine et animale au Tchad : contribution à la mise en évidence et caractérisation des agents causaux et leur implication en santé publique [PDF]
Chad is a high-incidence country for clinical tuberculosis. Within the last decade, the annual incidence rate increased from 120 human tuberculosis cases per 100’000 people to 370/100’000 in 2004.
Diguimbaye, Colette
core +1 more source
Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer [PDF]
Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community.
Emma L. Doughty +17 more
core +2 more sources
A case report of cutaneous infection with Mycobacterium neoaurum
Key Clinical Message Cutaneous infection due to Mycobacterium neoaurum in immune‐competent individuals had only been reported in limited cases. The point that makes our case very impressive was its cutaneous infection, and presentation in the immune ...
Alireza Mohebbipour‐Loren +3 more
doaj +1 more source
An Unusual Case of a Cervical Mass Due to Nontuberculous Mycobacterium Fortuitum Infection [PDF]
Mycobacterium fortuitum, of the class of nontuberculous mycobacteria, rarely causes cervical lymphadenopathy and head and neck masses. However, we treated a woman with a neck mass that was indeed caused by a mycobacterial infection. Our case is unique in that prompt recognition of the infection and treatment with antimicrobials averted surgery ...
Hien, Nguyen, Connie, Le, Hanh, Nguyen
openaire +2 more sources

