Treatment of Mycobacterium abscessus Complex [PDF]
AbstractOf the nontuberculous mycobacteria (NTMs) causing lung disease, members of the Mycobacterium abscessus complex (MABc) present a formidable obstacle to successful management. This challenge starts from a poorly understood pathogenesis, continues with complicated subspecies variation in treatment response, and extends to the multidrug-resistant ...
Luke, Strnad, Kevin L, Winthrop
openaire +2 more sources
In vitro activity of bedaquiline against rapidly growing nontuberculous mycobacteria [PDF]
Bedaquiline (BDQ) has been proven to be effective in the treatment of multidrug-resistant tuberculosis. We hypothesized that BDQ could be a potential agent to treat nontuberculous mycobacterial (NTM) infection. The objective of this study was to evaluate
Aguilar-Ayala, Diana +7 more
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Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]
Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul +2 more
core +1 more source
Complete Genome Sequences of Mycobacterium smegmatis Phages NihilNomen and Carlyle, Isolated in Las Vegas, Nevada [PDF]
We present the complete genomes of the Mycobacterium smegmatis phages Carlyle and NihilNomen, isolated from soil in Las Vegas, Nevada. The phages were isolated and annotated by undergraduate students enrolled in the Phage Discovery course offered by the ...
Bhatti, Khadija +22 more
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Mycobacterium abscessus, which is ubiquitous environmental organism, is more likely to cause pulmonary infection in the presence underlying lung disease and immunosuppression.
Celestine Ishiekwene +5 more
doaj +1 more source
The heterogenous and diverse population of prophages in Mycobacterium genomes
Bacterial genomes commonly carry one or more integrated prophages, although prophage prevalence varies greatly in different bacterial genera and species.
Lawrence Abad +4 more
doaj +1 more source
Probable disseminated Mycobacterium abscessus subspecies bolletii infection in a patient with idiopathic CD4+ T lymphocytopenia: a case report. [PDF]
INTRODUCTION: Rapidly growing mycobacteria are opportunistic pathogens in patients with underlying riskfactors. Mycobacterium abscessus subsp. bolletii is a newly recognized member of rapidlygrowing mycobacteria, isolated from respiratory tract and ...
BONURA, Celestino +7 more
core +2 more sources
Treatment ofMycobacterium abscessusInfection [PDF]
Mycobacterium abscessus is often resistant to multiple antimicrobial drugs, and data supporting effective drugs or dosing regimens are limited. To better identify treatment approaches and associated toxicities, we collected a series of case reports from the Emerging Infections Network. Side effects were common and often led to changing or discontinuing
Shannon A. Novosad +4 more
openaire +3 more sources
Population heterogeneity in Mycobacterium smegmatis and Mycobacterium abscessus
Bacteria use population heterogeneity, the presence of more than one phenotypic variant in a clonal population, to endure diverse environmental challenges – a ‘bet-hedging’ strategy. Phenotypic variants have been described in many bacteria, but the phenomenon is not well-understood in mycobacteria, including the environmental factors that influence ...
Sarah E. M. Born +5 more
openaire +2 more sources
A Case of Multiple Skin Lesions After LipodissolveTM Injection
Mycobacterium abscessus (M. abscessus) is a rapidly growing nontuberculous mycobacterium commonly found in soil and water. It can cause localized infection when inoculated during surgical or cosmetic procedures.
Peihsuan R. Tsai +7 more
doaj +1 more source

